NCT05969795 Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase Support
| NCT ID | NCT05969795 |
| Status | Recruiting |
| Phase | Phase 1 |
| Sponsor | ART Fertility Clinics LLC |
| Condition | Pregnancy Related |
| Study Type | INTERVENTIONAL |
| Enrollment | 342 participants |
| Start Date | 2023-09-05 |
| Primary Completion | 2026-04-30 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
To evaluate whether single euploid embryo transfer in NC without routinely administered LPS is non-inferior to NC with routinely administered LPS.
Eligibility Criteria
Inclusion Criteria: * Age: 18 to 40 years * Regular ovulatory cycles * Availability of at least one euploid embryo after Trophectoderm biopsy for PGT-A on day 5 or day 6 * Detection of ovulation by P4 rise \> 1.0 ng/ml after LH surge * P4 value of at least 5 ng/ml on day 4 after ovulation Exclusion Criteria: * History of repeated pre-menstrual spotting * Factors affecting the implantation through anatomical changes of the uterus / ovaries or the tubes (adenomyosis, Asherman syndrome, endometriosis, uterine fibroids / polyps, isthmocele with intracavitary fluid presence, hydrosalpinx….)