NCT07535177 Gas6 and Soluble MerTK in Periodontal Diseases
| NCT ID | NCT07535177 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Abant Izzet Baysal University |
| Condition | Periodontitis |
| Study Type | OBSERVATIONAL |
| Enrollment | 90 participants |
| Start Date | 2026-03-25 |
| Primary Completion | 2026-05-10 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 90 participants in total. It began in 2026-03-25 with a primary completion date of 2026-05-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aimed to investigate gingival crevicular fluid (GCF) and serum soluble MerTK (sMerTK) and Gas6 levels in periodontal health and disease. A total of 90 individuals, 30 patients with stage III grade B periodontitis, 30 with gingivitis and 30 periodontally healthy individuals were included. Whole-mouth and site-specific clinical periodontal parameters including probing depth, clinical attachment level, bleeding on probing, gingival index, plaque index were recorded. GCF and serum sMerTK and Gas6 levels were measured by enzyme-linked immunosorbent assay. Statistical analysis was performed by using non-parametric tests.
Eligibility Criteria
Inclusion Criteria: * Individuals without systemic diseases that may affect periodontal tissues (such as cardiovascular diseases, atherosclerosis, immune system disorders, rheumatoid arthritis, obesity, cancer, and diabetes) * Individuals who have not used antibiotics within the last 3 months * Individuals not taking any medications known to affect periodontal tissues * Individuals without infectious diseases such as HIV, hepatitis B virus (HBV), or tuberculosis * Individuals with at least 16 natural teeth, excluding third molars * Individuals aged 18 years and older Exclusion Criteria: * Pregnant or lactating individuals * Individuals who have received periodontal treatment within the last 6 months * Current smokers
Frequently Asked Questions
Who can join the NCT07535177 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Periodontitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07535177 currently recruiting?
Yes, NCT07535177 is actively recruiting participants. Visit ClinicalTrials.gov or contact Abant Izzet Baysal University to inquire about joining.
Where is the NCT07535177 trial being conducted?
This trial is being conducted at Bolu, Turkey (Türkiye).
Who is sponsoring the NCT07535177 clinical trial?
NCT07535177 is sponsored by Abant Izzet Baysal University. The trial plans to enroll 90 participants.