NCT06958874 Adjunctive Effect of Erythritol on Pocket Closure Rates
| NCT ID | NCT06958874 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of L'Aquila |
| Condition | Periodontitis |
| Study Type | INTERVENTIONAL |
| Enrollment | 56 participants |
| Start Date | 2024-11-08 |
| Primary Completion | 2025-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 56 participants in total. It began in 2024-11-08 with a primary completion date of 2025-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This clinical trial is studying whether using erythritol powder during non-surgical periodontal treatment (deep cleaning) helps improve gum health in people with severe periodontitis. Participants with deep gum pockets (4 mm or more) receive standard treatment alone or standard treatment plus cleaning with erythritol powder. The goal is to evaluate if adding erythritol improves outcomes such as healing of gum pockets, bleeding, plaque levels, and gum attachment compared to standard treatment alone.
Eligibility Criteria
Inclusion Criteria: Adults aged 18 years or older Diagnosed with stage 3 or 4 periodontitis according to the 2017 classification Presence of at least 12 natural teeth Presence of periodontal pockets with probing depth ≥ 4 mm in non-adjacent teeth Good general health or stable systemic conditions (e.g., controlled diabetes) Exclusion Criteria: Use of antibiotics or anti-inflammatory drugs within 3 months prior to treatment Periodontal treatment in the previous 6 months Pregnancy or breastfeeding Current smokers of more than 10 cigarettes per day Allergies or intolerance to erythritol or any materials used in the treatment Systemic diseases or conditions that could influence periodontal healing (e.g., uncontrolled diabetes, immunodeficiency) Use of medications known to affect periodontal tissues (e.g., phenytoin, cyclosporine, calcium channel blockers)
Frequently Asked Questions
Who can join the NCT06958874 clinical trial?
This trial is open to participants of all sexes, aged 35 Years or older, studying Periodontitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06958874 currently recruiting?
Yes, NCT06958874 is actively recruiting participants. Visit ClinicalTrials.gov or contact University of L'Aquila to inquire about joining.
Where is the NCT06958874 trial being conducted?
This trial is being conducted at L’Aquila, Italy.
Who is sponsoring the NCT06958874 clinical trial?
NCT06958874 is sponsored by University of L'Aquila. The trial plans to enroll 56 participants.