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Recruiting NCT04422405

NCT04422405 Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB

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Clinical Trial Summary
NCT ID NCT04422405
Status Recruiting
Phase
Sponsor Spital Limmattal Schlieren
Condition Obesity, Morbid
Study Type INTERVENTIONAL
Enrollment 300 participants
Start Date 2020-06-01
Primary Completion 2035-05-28

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 65 Years
Study Type INTERVENTIONAL
Interventions
One Anastomosis Gastric Bypass (OAGB)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 300 participants in total. It began in 2020-06-01 with a primary completion date of 2035-05-28.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Evaluation of the functional changes in the stomach and esophagus of patients undergoing One Anastomosis Gastric Bypass (OAGB)

Eligibility Criteria

Inclusion Criteria: * BMI\> 35 kg/m2 * 2 years of controlled conservative obesity treatment without weight reduction * patients should give their consent to participate in the study Exclusion Criteria: * Less than 2 years of conservative obesity treatment * cancer * cirrhosis Child-Pough score A * Crohn's disease * serious psychiatric disorder, which led to in-hospital treatment in psychiatric clinic in the past two years * drug consumption * non-compliance * hiatal hernia \> 4cm * gastric pouch \< 10cm * Barett esophagus * erosive esophagitis Grade C or D according to the Los Angeles Classification * endoscopically proven gastric stricture * acid exposition time \> 6% (Lyon criteria) * reflux episodes\> 80 /24 hours (Lyon criteria) * insufficient low esophageal sphincter according to manometry findings * pathological findings in the impedance pH-metry (acid and non-acid reflux)

Contact & Investigator

Central Contact

Urs Zingg, MD, Prof.

✉ urs.zingg@spital-limmattal.ch

📞 +41 44 733 21 26

Frequently Asked Questions

Who can join the NCT04422405 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Obesity, Morbid. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04422405 currently recruiting?

Yes, NCT04422405 is actively recruiting participants. Contact the research team at urs.zingg@spital-limmattal.ch for enrollment information.

Where is the NCT04422405 trial being conducted?

This trial is being conducted at Schlieren, Switzerland.

Who is sponsoring the NCT04422405 clinical trial?

NCT04422405 is sponsored by Spital Limmattal Schlieren. The trial plans to enroll 300 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology