NCT06493227 Extended Perioperative Administration of Fibrinolysis Inhibitors After Cardiac Surgery
| NCT ID | NCT06493227 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Saint Petersburg State University, Russia |
| Condition | Thoracic Surgery |
| Study Type | INTERVENTIONAL |
| Enrollment | 1,373 participants |
| Start Date | 2024-08-01 |
| Primary Completion | 2025-12-30 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
PRIORITY is a pragmatic, multi-center, cluster crossover trial that aims to evaluate whether implementing a policy of routine extended (intraoperative and 4 hour after transfer to ICU) use of fibrinolysis inhibitors leads to a decrease in post-operative blood transfusion compared to a policy that only involves intraoperative use.
Eligibility Criteria
Inclusion Criteria: 1. A hospital that performs a minimum of 250 open heart interventions per year. 2. Consent from hospital physicians regarding the prophylactic use of fibrinolysis inhibitors (more than 95% of physicians involved in the treatment of adult patients (\>18 years) agree to adhere to the strategy of using fibrinolysis inhibitors as prescribed by the study protocol). Exclusion Criteria: * Hospital does not meet inclusion criteria