NCT06774248 Expanding the Youth Opioid Recovery Support (YORS) Intervention for MOUD Adherence to Adolescents With OUD
| NCT ID | NCT06774248 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Potomac Health Foundations |
| Condition | Opioid Use Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2025-02-01 |
| Primary Completion | 2027-07-01 |
Trial Parameters
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Brief Summary
Despite rising rates of fatal opioid overdoses in the United States, adolescents with OUD are far less likely than adults to receive and be retained on medication for opioid use disorder (MOUD). The multicomponent Youth Opioid Recovery Support (YORS) intervention for young adults seeks to increase adherence to extended-release MOUD and reduce opioid relapse through family involvement, assertive outreach, low-barrier access to MOUD, and contingency management. By expanding investigations of the evidence based YORS intervention to adolescents, especially those on sublingual buprenorphine, this project will significantly contribute to our knowledge base of practical strategies to address the opioid crisis in youth.
Eligibility Criteria
Inclusion Criteria for adolescent patients with OUD: 1. English speaking 2. Provision of signed and dated informed assent form (may be collected verbally over audio and/or video platform in the event of a remote enrollment) 3. Willing to have a legal, English-speaking guardian provide informed consent (may be collected verbally over audio and/or video platform in the event of a remote enrollment) 4. Stated willingness to comply with all study procedures and the YORS intervention 5. Age 13-21 (inclusive) 6. Documented diagnosis of opioid use disorder (OUD) 7. Presenting for an index episode of inpatient or outpatient treatment at Maryland Treatment Centers with at least one day of opioid use in the 30 days prior to enrollment 8. Considering treatment with XR-NTX, XR-BUP, or SL-BUP\* OR has begun SL-BUP maintenance treatment within the past two weeks 9. Willing to designate a parent, family member, or other person to be involved in their OUD treatment as a Treatment Significant Other 10.