← Back to Clinical Trials
Recruiting NCT04355572

NCT04355572 Evaluation of the Clinical and Psychological Impact of Vitamin D Replacement in Adolescent Females at Risk for Polycystic Ovarian Syndrome (PCOS)

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT04355572
Status Recruiting
Phase
Sponsor Yale University
Condition Polycystic Ovarian Syndrome in Adolescent Females
Study Type INTERVENTIONAL
Enrollment 60 participants
Start Date 2026-05
Primary Completion 2027-12-01

Eligibility & Interventions

Sex Female only
Min Age 13 Years
Max Age 21 Years
Study Type INTERVENTIONAL
Interventions
Vitamin D 4000IU dailyPlacebo

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 60 participants in total. It began in 2026-05 with a primary completion date of 2027-12-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study is a double blind, placebo controlled, randomized trial of study subjects with PCOS and low vitamin D to 2 groups- placebo and vitamin D replacement. Participants and investigators will be blinded to treatment modality until the end of the trial period

Eligibility Criteria

Inclusion Criteria: \- Postmenarchal adolescent females aged 13-21 who meet modified Rotterdam criteria for PCOS, with a serum vitamin D level between 6-29 ng/mL. Exclusion Criteria: * Other causes for hyperandrogenism, * Chronic renal diseases, * Acquired or inherited calcium and vitamin D metabolic disorders.

Contact & Investigator

Central Contact

Alla Vash-Margita, MD

✉ alla.vash-margita@yale.edu

📞 203-785-4010

Principal Investigator

Alla Vash-Margita, MD

PRINCIPAL INVESTIGATOR

Yale University

Frequently Asked Questions

Who can join the NCT04355572 clinical trial?

This trial is open to female participants only, aged 13 Years or older, up to 21 Years, studying Polycystic Ovarian Syndrome in Adolescent Females. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04355572 currently recruiting?

Yes, NCT04355572 is actively recruiting participants. Contact the research team at alla.vash-margita@yale.edu for enrollment information.

Where is the NCT04355572 trial being conducted?

This trial is being conducted at New Haven, United States.

Who is sponsoring the NCT04355572 clinical trial?

NCT04355572 is sponsored by Yale University. The principal investigator is Alla Vash-Margita, MD at Yale University. The trial plans to enroll 60 participants.

Related Trials

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology