NCT06490679 Evaluation Of Nonsurgical Treatment Of Deep Periodontal Pockets (7-10mm) Using AIRFLOW® Prophylaxis Master Device With Erythritol Powder vs Conventional Instrumentation
| NCT ID | NCT06490679 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Cairo University |
| Condition | Periodontal Pocket |
| Study Type | INTERVENTIONAL |
| Enrollment | 46 participants |
| Start Date | 2024-03-01 |
| Primary Completion | 2025-06-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 46 participants in total. It began in 2024-03-01 with a primary completion date of 2025-06-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Periodontitis is a chronic condition associated with the inflammatory destruction of the periodontal tissues ultimately leading to tooth loss. Clinically, it is identified by key features such as clinical attachment loss (CAL), bleeding upon probing (BOP), and an increase in probing pocket depth (PPD), and/or gingival recession. Periodontitis is mediated by polymicrobial dysbiosis with keystone pathogens affecting the virulence of the entire biofilm community. The removal of this biofilm and its retention factors is the ultimate goal of clinical treatment and oral measures applied. The elimination of the biofilm has traditionally been achieved with the use of either hand instruments or power driven devices. Promoting periodontal health or diminishing bacterial presence and calculus buildup on teeth can be accomplished with the same efficacy whether using manual scalers and curettes or ultrasonic scaling instruments. Both hand and ultrasonic instruments are characterized by being time- consuming and requiring technical skill, often causing patient discomfort and post-treatment pain, including hypersensitivity resulting from the loss of hard tissue when scaling the tooth surface. Ultrasonic instruments tend to leave a rougher surface behind compared to hand instruments. While effective the current techniques all have their disadvantages. The aim of this study is to evaluate changes in probing depth clinically, Bleeding on probing, Clinical attachment level, Plaque index, Calculus index, Patient pain/discomfort, Patient satisfaction, Cost effectiveness, Treatment time and Number of pockets closed after using AIRFLOW® Prophylaxis Master device with erythritol powder.
Eligibility Criteria
Inclusion Criteria: * Systemically healthy patients. * Patients with an age range between 16 to 80 years. * Patients have a minimum of 20 teeth. * Periodontitis patients with at least one residual pocket with a probing depth ranging from 7 to 10 mm. * Cooperative patients able and willing to come for follow up appointments. Exclusion Criteria: * Pregnant and lactation females. * Patients reporting systemic conditions (eg: diabetes). * Patients with severe or unstable upper respiratory tract infections, chronic bronchitis/asthma. * Patients with severe inflammation and/or osteonecrosis.
Contact & Investigator
Hani El-Nahas, Professor
STUDY DIRECTOR
Cairo University
Frequently Asked Questions
Who can join the NCT06490679 clinical trial?
This trial is open to participants of all sexes, aged 16 Years or older, up to 80 Years, studying Periodontal Pocket. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06490679 currently recruiting?
Yes, NCT06490679 is actively recruiting participants. Contact the research team at mohammad.alaa@dentistry.cu.edu.eg for enrollment information.
Where is the NCT06490679 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT06490679 clinical trial?
NCT06490679 is sponsored by Cairo University. The principal investigator is Hani El-Nahas, Professor at Cairo University. The trial plans to enroll 46 participants.