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Recruiting NCT07653490

NCT07653490 Erector Spinae Plane Block and Low-Flow Anaesthesia in Laparoscopic Cholecystectomy

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Clinical Trial Summary
NCT ID NCT07653490
Status Recruiting
Phase
Sponsor Taksim Egitim ve Arastirma Hastanesi
Condition Postoperative Pain
Study Type INTERVENTIONAL
Enrollment 72 participants
Start Date 2026-06-18
Primary Completion 2027-05-18

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 65 Years
Study Type INTERVENTIONAL
Interventions
Erector Spinae Plane BlockLow Fresh Gas Flow (0.5 L/min)Standard Fresh Gas Flow (3 L/min)

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 72 participants in total. It began in 2026-06-18 with a primary completion date of 2027-05-18.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This prospective randomized controlled study aims to evaluate the effects of preoperative ultrasound-guided erector spinae plane (ESP) block combined with low-flow anaesthesia on postoperative quality of recovery and opioid consumption in patients undergoing elective laparoscopic cholecystectomy. The study will compare postoperative recovery quality, pain scores, analgesic requirements, and perioperative outcomes between patients receiving ESP block with low-flow anaesthesia and those receiving standard anaesthetic management.

Eligibility Criteria

Inclusion Criteria: * Patients aged 18-65 years * ASA physical status I-II * Body mass index (BMI) \<35 kg/m² * Scheduled for elective laparoscopic cholecystectomy * Ability to provide written informed consent Exclusion Criteria: * Coagulopathy or bleeding disorders * Allergy to local anaesthetic agents * Infection at the block application site * Neurological or psychiatric disorders * Communication difficulties * Chronic opioid or analgesic use * Reoperation cases * Acute cholecystitis * Conversion to open surgery * Inadequate dermatomal block after ESPB * Severe intraoperative hemodynamic instability * Intraoperative blood loss ≥250 mL * Development of allergic reactions or major complications during follow-up

Contact & Investigator

Central Contact

Leyla Sivacigil, MD

✉ veralleyla@hotmail.com

📞 90 5065983478

Principal Investigator

Leyla SIVACIGIL, MD

PRINCIPAL INVESTIGATOR

Taksim Training and Research Hospital

Frequently Asked Questions

Who can join the NCT07653490 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Postoperative Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07653490 currently recruiting?

Yes, NCT07653490 is actively recruiting participants. Contact the research team at veralleyla@hotmail.com for enrollment information.

Where is the NCT07653490 trial being conducted?

This trial is being conducted at Istanbul, Turkey (Türkiye).

Who is sponsoring the NCT07653490 clinical trial?

NCT07653490 is sponsored by Taksim Egitim ve Arastirma Hastanesi. The principal investigator is Leyla SIVACIGIL, MD at Taksim Training and Research Hospital. The trial plans to enroll 72 participants.

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