NCT06555107 Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery
| NCT ID | NCT06555107 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Centre Hospitalier Universitaire, Amiens |
| Condition | Chronic Postsurgical Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 693 participants |
| Start Date | 2024-08-29 |
| Primary Completion | 2027-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 693 participants in total. It began in 2024-08-29 with a primary completion date of 2027-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Studies evaluating postoperative pain as a risk factor for CPSP are almost exclusively carried out in the context of scheduled surgery. As a result, the preoperative pain studied as a risk factor for chronicity is essentially a state of pain that has persisted for several weeks or even several months. In emergency surgeries, patients are subject to acute preoperative pain of varying intensity and the duration of which may vary by a few days. A few studies have highlighted the intensity of acute preoperative pain as a factor favouring moderate to severe postoperative pain. At this point, no study has addressed the long-term consequences of this intense preoperative pain the emergency context. An evaluation in the field of emergency surgery, where the preoperative pain is often intense and limited in time, would enable us to identify more precisely the impact of acute pain on the incidence of CPSP. The investigators are hypothesising that the occurrence of CPSP at 3 months in patients undergoing emergency orthopaedic or abdominal surgery is associated with acute preoperative pain.
Eligibility Criteria
Inclusion Criteria: * Age ≥18 years old. * Emergency orthopaedic and/or abdominal surgery. * Informed consent. * Affiliation to a social security scheme Exclusion Criteria: * Intraoperative complications that are life-threatening or require the surgical procedure to be discontinued. * Post-operative intensive care unit admission. * Ambulatory surgery. * Endoscopic surgery. * Repeat surgery at the same site in less that 3months. * Pregnant or breast-feeding patients. * Patients under guardianship or deprived of liberty. * Patients suffering from psychiatric pathologies. * Patients suffering from neurodegenerative pathologies. * Patients for whom self-assessment of pain using a numerical scale (0-10) cannot be carried out (non-communicative patients, non-French-speaking patients, and so on).
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06555107 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Chronic Postsurgical Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06555107 currently recruiting?
Yes, NCT06555107 is actively recruiting participants. Contact the research team at Tarpin.Paul@chu-amiens.fr for enrollment information.
Where is the NCT06555107 trial being conducted?
This trial is being conducted at Amiens, France.
Who is sponsoring the NCT06555107 clinical trial?
NCT06555107 is sponsored by Centre Hospitalier Universitaire, Amiens. The trial plans to enroll 693 participants.