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Recruiting NCT04230616

NCT04230616 Efficacy and Safety of NAVIO

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Clinical Trial Summary
NCT ID NCT04230616
Status Recruiting
Phase
Sponsor Sint-Trudo Hospital
Condition Osteoarthritis, Knee
Study Type INTERVENTIONAL
Enrollment 180 participants
Start Date 2021-02-01
Primary Completion 2022-02

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
total knee arthroplastyCT scan

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 180 participants in total. It began in 2021-02-01 with a primary completion date of 2022-02.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of the study is to compare the efficacy, safety and costs of the NAVIO™ system with the conventional intramedullary alignment guide for total knee replacement in a clinical setting. The hypothesis is that total knee arthroplasty (TKA) with the use of NAVIO™ is at least as efficient and safe as TKA with the use of conventional intramedullary alignment guiding.

Eligibility Criteria

Inclusion Criteria: * Painful and disabled knee joint resulting from osteoarthritis where one or more compartments are involved, as assessed by X-ray * High need to obtain pain relief and improve function * Above 18 years old * Able and willing to follow instructions * Informed consent Exclusion Criteria: * Active infection in knee * General infection * Failure of previous joint replacement * Post-operative or post traumatic malalignment of the knee/leg * Pregnancy * Not able or willing to undergo CT-scan

Contact & Investigator

Central Contact

Peter Bollars, Dr.

✉ peter.bollars@stzh.be

📞 +3211 33 42 86

Principal Investigator

Peter Bollars, Dr.

PRINCIPAL INVESTIGATOR

Orthopedic Association Sint-Trudo Hospital

Frequently Asked Questions

Who can join the NCT04230616 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Osteoarthritis, Knee. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04230616 currently recruiting?

Yes, NCT04230616 is actively recruiting participants. Contact the research team at peter.bollars@stzh.be for enrollment information.

Where is the NCT04230616 trial being conducted?

This trial is being conducted at Sint-Truiden, Belgium.

Who is sponsoring the NCT04230616 clinical trial?

NCT04230616 is sponsored by Sint-Trudo Hospital. The principal investigator is Peter Bollars, Dr. at Orthopedic Association Sint-Trudo Hospital. The trial plans to enroll 180 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology