Effects of Transcranial Magnetic Stimulation After Endovascular Treatment for Acute Ischemic Stroke
Trial Parameters
Brief Summary
This is a multicenter, randomized, double-blind, sham-controlled trial, to determine the efficacy and safety of cTBS in treating patients with acute ischemic stroke after endovascular treatment.
Eligibility Criteria
Inclusion Criteria: 1. Patients with acute anterior circulation ischemic stroke aged between 18 and 80 years old. 2. Imaging suggests that the infarction is caused by occlusion of the terminal portion of the internal carotid artery or the M1/M2 segment of the middle cerebral artery. 3. A head CT within 24 hours of onset indicates an ASPECT score ≥6, and meets the guideline-recommended criteria for thrombectomy. 4. Pre-stroke mRS score is ≤1. 5. NIHSS score before thrombectomy is between 6 and 25. 6. With vascular recanalization of mTICI \> 2b/3. 7. Informed consent form signed. Exclusion Criteria: 1. Patients with contraindications to TMS treatment, such as those with metallic foreign objects in the head, pacemakers, implantable drug pumps, cochlear implants, etc.; 2. Patients with epilepsy, increased intracranial pressure, tumors, acute cerebral hemorrhage, or other severe neurological diseases, and those with severe functional impairment of organs such as the heart, liver, and kidney