NCT06679543 Effects of Partial Sleep Deprivation on Cardiac Output During Cycling
| NCT ID | NCT06679543 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Guelph |
| Condition | Sleep Deprivation |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-01-02 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-01-02 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to determine if attenuations in cardiac output drive the blunted blood pressure response during cycling exercise following a night of partial sleep deprivation in young healthy adults (%50 females). The secondary outcome is to assess sex differences. The main questions it aims to answer are: * Do reductions in plasma volume drive reductions in cardiac output and therefore blood pressure during exercise following a night of partial sleep deprivation? * Do sex differences exist? Participants will: * Visit the lab after a night of normal sleep and a night of partial sleep deprivation. * Keep a daily diary of their sleep and food/beverage intake. * Perform maximal and submaximal exercise on a cycle ergometer.
Eligibility Criteria
Inclusion Criteria: * Free of known cardiovascular or metabolic diseases or sleep disorders * No history of smoking (within the past 3 months) * Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+) * No prescription of chronic medications other than oral contraceptives * Able to abide by sleep protocols for all visits * Individuals who are not allergic to ultrasound gel * Individuals who are not pregnant Exclusion Criteria: * Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders * Has a history of smoking (within the past 3 months) * Not ready to engage in physical activity as assessed by the PAR-Q+ * Individuals prescribed chronic medications other than oral contraceptives * Unable to abide by sleep protocols for any testing visit * Allergic to ultrasound gel * Pregnancy
Contact & Investigator
Julian Bommarito, MSc
STUDY DIRECTOR
University of Guelph
Frequently Asked Questions
Who can join the NCT06679543 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 50 Years, studying Sleep Deprivation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06679543 currently recruiting?
Yes, NCT06679543 is actively recruiting participants. Contact the research team at jbomma01@uoguelph.ca for enrollment information.
Where is the NCT06679543 trial being conducted?
This trial is being conducted at Guelph, Canada.
Who is sponsoring the NCT06679543 clinical trial?
NCT06679543 is sponsored by University of Guelph. The principal investigator is Julian Bommarito, MSc at University of Guelph. The trial plans to enroll 30 participants.