NCT05932745 Effects of Novel E-cigarette Constituents on Adults TCORS 3.0
| NCT ID | NCT05932745 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Yale University |
| Condition | Nicotine Use Disorder |
| Study Type | INTERVENTIONAL |
| Enrollment | 66 participants |
| Start Date | 2025-06-20 |
| Primary Completion | 2026-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 66 participants in total. It began in 2025-06-20 with a primary completion date of 2026-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study is an examination of the influence of cooling components of WS-3, WS-23, and menthol on the appeal and addiction potential of nicotine-containing e-liquids among adults.
Eligibility Criteria
Inclusion Criteria: * 18 years or older * Able to read and write * Some current e-cigarette use * Urine cotinine ≥200ng/ml * Willing to abstain from tobacco/nicotine use 2 hours prior to sessions Exclusion Criteria: * Current use of non-prescription substances besides nicotine, marijuana, alcohol * Any significant current medical or psychiatric condition * Known hypersensitivity to propylene glycol * Pregnant or lactating females * Uncontrolled asthma * Nut/e-liquid flavorant allergy * Current marijuana (tetrahydrocannabinol) vaping + E-cigarette or vaping use Associated Lung Injury (EVALI) symptoms * Dislike of menthol flavor
Contact & Investigator
Suchitra Krishnan-Sarin, PhD
PRINCIPAL INVESTIGATOR
Yale University
Frequently Asked Questions
Who can join the NCT05932745 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Nicotine Use Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05932745 currently recruiting?
Yes, NCT05932745 is actively recruiting participants. Contact the research team at danielle.davis@yale.edu for enrollment information.
Where is the NCT05932745 trial being conducted?
This trial is being conducted at New Haven, United States.
Who is sponsoring the NCT05932745 clinical trial?
NCT05932745 is sponsored by Yale University. The principal investigator is Suchitra Krishnan-Sarin, PhD at Yale University. The trial plans to enroll 66 participants.