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Recruiting NCT06723626

Effects of Intravenous Metabolic Recovery Agent in Elderly Septic Patients on Prognosis and Microcirculation.

Trial Parameters

Condition Septic Shock
Sponsor Southeast University, China
Study Type INTERVENTIONAL
Phase N/A
Enrollment 40
Sex ALL
Min Age 60 Years
Max Age 85 Years
Start Date 2024-07-01
Completion 2025-11-30
Interventions
Metabolic resuscitation agentHydrocortisone

Brief Summary

This study intends to observe the effect of intravenous hydrocortisone combined with vitamin C and vitamin B1 infusion on the prognosis and sublingual microcirculation in patients with sepsis or septic shock through a prospective randomized controlled study method.

Eligibility Criteria

Inclusion Criteria: * Age ≥60 and ≤85 years old; * Diagnosis of sepsis or septic shock; * Clinical judgment for hydrocortisone treatment; * Signing Informed Consent. Exclusion Criteria: * patients in palliative care; * uncontrolled malignancy with multiple metastases; * ineffective surgical intervention for the infectious agent; * estimated death within 24 hours; * glucocorticoids used in the last 7 days; * allergy to hydrocortisone, vitamin c or vitamin B1; * inability to measure sublingual microcirculation.

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