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Recruiting NCT07073235
Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients
Trial Parameters
Condition Stroke
Sponsor Danderyd Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 56
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-11
Completion 2030-12
All Conditions
Interventions
Intermittent Theta Burst StimulationSham Intermittent Theta Burst Stimulation
Brief Summary
This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower extremity in the chronic phase after stroke. It also seeks to explore the underlying mechanisms by investigating changes of functional and structural brain networks.
Eligibility Criteria
Inclusion Criteria: * Age over 18 * Chronic stroke (\>6 months) * Residual hemiparesis FAC ≥3 Exclusion Criteria: * Metal implants * Epilepsy/seizures * Pregnancy * Claustrophobia (related to MRIs exams) * Severe cognitive impairment * Untreated or unstable depression/anxiety * Other disabilities prohibiting intensive physical training
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