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Recruiting NCT05993221

Deconstructing Post Stroke Hemiparesis

Trial Parameters

Condition Stroke
Sponsor Providence VA Medical Center
Study Type OBSERVATIONAL
Phase N/A
Enrollment 75
Sex ALL
Min Age 18 Years
Max Age 90 Years
Start Date 2023-09-05
Completion 2027-09

Brief Summary

TRACTs (DeconsTructing Post StRoke HemipAresis for PreCision NeurorehabiliTation) is a single timepoint study that aims to deconstruct post-stroke deficits of the upper extremity into distinct components and relate these components to brain anatomy and physiology.

Eligibility Criteria

Inclusion Criteria: * Diagnosis of a unilateral ischemic stroke occurring \>6 months prior as documented in medical chart * Upper extremity motor impairment as measured by Fugl-Meyer Upper Extremity Assessment ≤60 * Ability to follow simple instructions in English Exclusion Criteria: * Greater than moderate difficulty using the arm and hand pre-dating the stroke as assessed by the questions adapted from the QuickDASH outcome measure score on any question \>= 3, which measures physical function and symptoms in people with difficulty using the arm and hand. * Visual or auditory disorders resulting in the inability to see or hear, respectively, the stimuli presented as part of research sessions * Inability to maintain a seated position for at least one hour * Standard MRI exclusion (e.g., significant claustrophobia or inability to tolerate loud noises, cardiac pacemaker (unless MRI-safe), implanted device (deep brain stimulation) or metal in the brain, cervical spinal cord, or upper thora

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