NCT06187038 Effects of Including a Chronic Pain Neuroscience Education Program for Individuals With Knee OA
| NCT ID | NCT06187038 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Nove de Julho |
| Condition | Osteoarthritis, Knee |
| Study Type | INTERVENTIONAL |
| Enrollment | 92 participants |
| Start Date | 2024-05-28 |
| Primary Completion | 2026-11-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 92 participants in total. It began in 2024-05-28 with a primary completion date of 2026-11-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Research participants diagnosed with knee osteoarthritis will be randomized through a draw using sealed opaque envelopes indicating two groups: 1. therapeutic exercises, 2. therapeutic exercises + chronic pain neuroscience education program. The primary outcome will be functional performance using a patient-reported measure, the Knee Injury and Osteoarthritis Outcome Score (KOOS). The selected secondary outcomes will be pain intensity by the numerical pain scale (END), physical function reported by the patient by the patient-specific functional scale (EFEP), Pain self-efficacy questionnaire (PSEQ), functional mobility by the timed up and test (TUG), general effect perceived through the global perception scale (EPG), muscle strength through Maximum Voluntary Isometric Contraction (MVIC) and functionality and disability through the World Health Organization Disability Assessment Schedule (WHODAS).
Eligibility Criteria
Inclusion Criteria: * A clinical diagnosis of knee osteoarthritis (knee pain for \> 3 months * Morning stiffness \<30 minutes * Crepitus * Bone tenderness, and absence of palpable heat and/or diagnosis established radiographically (determined by Kellgren and Lawrence grade 1 to 3 on a scale 1 up to 4) Exclusion Criteria: * Hip OA * severe osteoporosis * Fibromyalgia * Medical history of tumors or cancer * Active inflammatory joint diseases (rheumatoid arthritis, gout) * Undergoing any lower extremity joint replacement * Neurological diseases (Parkinson's disease, stroke, Multiple Sclerosis, muscular dystrophy, motor neuron disease, Alzheimer's disease, cognitive and cardiopulmonary impairment that may prevent or limit the performance of exercises, use of a gait assistance device, history of recent knee trauma. * Having undergone any form of treatment involving physiotherapy, intra-articular corticosteroids, anti-inflammatories or chondroprotective in the last six months
Contact & Investigator
Cid Gomes, PhD
PRINCIPAL INVESTIGATOR
Nove de Julho University
Frequently Asked Questions
Who can join the NCT06187038 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, up to 80 Years, studying Osteoarthritis, Knee. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06187038 currently recruiting?
Yes, NCT06187038 is actively recruiting participants. Contact the research team at cid.andre@gmail.com for enrollment information.
Where is the NCT06187038 trial being conducted?
This trial is being conducted at São Paulo, Brazil.
Who is sponsoring the NCT06187038 clinical trial?
NCT06187038 is sponsored by University of Nove de Julho. The principal investigator is Cid Gomes, PhD at Nove de Julho University. The trial plans to enroll 92 participants.