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Recruiting NCT07423767

NCT07423767 Effects of a Preoperative Cognitive-Behavioral Intervention on Kinesiophobia and Function in Anterior Cruciate Ligament Reconstruction

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Clinical Trial Summary
NCT ID NCT07423767
Status Recruiting
Phase
Sponsor Peking University Third Hospital
Condition Anterior Cruciate Ligament (ACL) Tear
Study Type INTERVENTIONAL
Enrollment 44 participants
Start Date 2026-02-14
Primary Completion 2027-06-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 45 Years
Study Type INTERVENTIONAL
Interventions
Cognitive-Behavioral InterventionControl group

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 44 participants in total. It began in 2026-02-14 with a primary completion date of 2027-06-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study aims to systematically elucidate the integrative effects of psychological rehabilitation on the "brain-psychology-motor" triad in patients with anterior cruciate ligament (ACL) rupture. We plan to recruit 44 patients (aged 18-45) diagnosed with ACL rupture and scheduled for reconstruction surgery at Peking University Third Hospital, who will be randomly assigned to two groups. Through synchronous acquisition of questionnaire scores, motor performance data (gait, jogging, postural stability), and central neural activity (EEG), this research seeks to establish a foundation for developing neuroscience evidence-based, precision rehabilitation strategies.

Eligibility Criteria

Inclusion Criteria: 1. Patients aged 18 to 45 years with a diagnosis of anterior cruciate ligament (ACL) rupture. 2. ACL rupture within 3 months prior to enrollment. 3. First-time ACL rupture with a scheduled reconstruction surgery at this institution. 4. The affected knee shows no significant redness, swelling, pain, or inflammation, with basic activities of daily living restored. 5. No injury or only mild (grade I) injury to the posterior cruciate ligament, medial collateral ligament, or lateral collateral ligament. Exclusion Criteria: 1. Body mass index (BMI) less than 18.5 or greater than 35 kg/m². 2. Age older than 45 years or younger than 18 years. 3. ACL rupture with a duration exceeding 3 months. 4. Concurrent severe injury (greater than grade I sprain) to the posterior cruciate ligament, medial collateral ligament, or lateral collateral ligament. (Note: Grade II indicates partial tear with ligament thickening, laxity, and partial fiber disruption; Grade III indicates complete rupture). 5. Concurrent severe meniscal tear. 6. History of prior knee surgery (e.g., meniscal repair, ligament reconstruction, joint replacement, arthroscopic debridement). 7. Presence of other significant knee pathologies, such as: knee osteoarthritis, knee tumor, rheumatoid arthritis, tuberculosis, or active infectious/inflammatory diseases of the knee. 8. Concurrent fracture, dislocation, or other osseous injuries involving the knee. 9. Unwillingness to receive the treatment protocol of this study.

Contact & Investigator

Central Contact

Shuang Ren, PhD

✉ xixishuang123@126.com

📞 17610252992

Frequently Asked Questions

Who can join the NCT07423767 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 45 Years, studying Anterior Cruciate Ligament (ACL) Tear. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07423767 currently recruiting?

Yes, NCT07423767 is actively recruiting participants. Contact the research team at xixishuang123@126.com for enrollment information.

Where is the NCT07423767 trial being conducted?

This trial is being conducted at Beijing, China, Beijing, China.

Who is sponsoring the NCT07423767 clinical trial?

NCT07423767 is sponsored by Peking University Third Hospital. The trial plans to enroll 44 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology