NCT07125313 Effect of Yoga Training on Cardiovascular and Mental Health Parameters in Hypertensive Patients
| NCT ID | NCT07125313 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Universidade Federal de Santa Catarina |
| Condition | Hypertension |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2025-08-11 |
| Primary Completion | 2026-12-20 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 70 participants in total. It began in 2025-08-11 with a primary completion date of 2026-12-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The objective of this study will be to analyze the effect of 16 weeks of Yoga training on cardiovascular, autonomic, mental health, and cognitive parameters in hypertensive individuals. This is a randomized, controlled clinical trial to be conducted with adults and elderly (40 years or older), of both sexes, diagnosed with High Blood Pressure (HBP), who will be randomized into two groups: Yoga Group (YG) and Control Group (CG). The YG will undergo a Yoga training program involving breathing techniques, mobility, physical postures, relaxation, and meditation for 16 weeks. In the first eight weeks (phase 1), three supervised weekly sessions will be held. In the last eight weeks of the study (phase 2), the training will consist of three supervised weekly sessions and the delivery of an asynchronous video lesson, with the weekly frequency then increasing (from three to four sessions per week). The video lesson will be available on a digital platform. Before, after eight weeks, and after 16 weeks, cardiovascular, autonomic, mental and cognitive health parameters will be assessed. Furthermore, the biomarkers Brain-Derived Neurotrophic Factor (BDNF), serotonin, and nitric oxide will be analyzed at different assessment times of the study, as well as biochemical profile tests (glucose, total cholesterol, among others), functional capacity tests, and body composition. This project is expected to contribute to the literature by better elucidating the effects of Yoga on the cardiovascular, mental, and cognitive health of hypertensive individuals. The SPSS (21.0) statistical package will be used for data analysis. After confirming the appropriate assumptions, generalized estimating equations will be used, followed by the Bonferroni post hoc test, with a significance level of 5%.
Eligibility Criteria
Inclusion Criteria: * Adults or elderly individuals * \>= 40 years * Both sexes * Diagnosis of hypertension controlled by up to three medications * Who do not present high cardiovascular risk * Who have not engaged in a physical exercise program in the six months prior to the start of the study will participate in the study. Exclusion Criteria: * Adherence of less than 75% of training sessions * Diagnosis of other diseases during the study * Adherence to another physical exercise program * Change in the class and/or dose of antihypertensive medication during the study * Worsening of the disease (resting systolic blood pressure (BP) \> 180 mmHg).
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07125313 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Hypertension. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07125313 currently recruiting?
Yes, NCT07125313 is actively recruiting participants. Contact the research team at alinegerage@yahoo.com.br for enrollment information.
Where is the NCT07125313 trial being conducted?
This trial is being conducted at Florianópolis, Brazil.
Who is sponsoring the NCT07125313 clinical trial?
NCT07125313 is sponsored by Universidade Federal de Santa Catarina. The trial plans to enroll 70 participants.