NCT07258875 Effect of VExUS Ultrasound Protocol (Venous Excess Ultrasound) on Perioperative Fluid Management, on the Incidence of Postoperative Pulmonary Complications and Postoperative Acute Kidney Injury in Patients Undergoing Thoracic Surgery
| NCT ID | NCT07258875 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Crete |
| Condition | Thoracic Surgery With One-lung Ventilation |
| Study Type | INTERVENTIONAL |
| Enrollment | 230 participants |
| Start Date | 2024-11-27 |
| Primary Completion | 2028-11-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 230 participants in total. It began in 2024-11-27 with a primary completion date of 2028-11-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to investigate the effect of a VExUS ultrasound guided protocol of perioperative fluid management within a goal-directed therapy framework, on postoperative respiratory complications, and the occurrence of acute kidney injury (AKI) in patients undergoing thoracic surgery.
Eligibility Criteria
Inclusion Criteria: * Adults \>18 years undergoing video assisted thoracic surgery/ lobectomy requiring one-lung ventilation. Exclusion Criteria: * Refusal to participate. * Pneumonectomy. * Young athletes (risk of physiologically large IVC \>2 cm). * Moderate-severe tricuspid regurgitation, moderate to severe pulmonary hypertension * Heart failure with reduced ejection fraction, EF\<35% * Portal hypertension, portal vein thrombosis, or liver cirrhosis. * Stage 4 or end-stage chronic kidney disease (eGFR \<30 mL/min/1.73 m² or dialysis). * Transfusion with more than 2 packed red blood cells unit perioperatively (intraoperatively, in the PACU, in the ward)
Contact & Investigator
Alexandros Bogas Manouselis, Resident of Anaesthesiology
✉ bogas.alexandros@gmail.com📞 +306947545446
Alexandra Papaioannou, Professor of Anaesthesiology
STUDY CHAIR
Medical School, University of Crete
Frequently Asked Questions
Who can join the NCT07258875 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Thoracic Surgery With One-lung Ventilation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07258875 currently recruiting?
Yes, NCT07258875 is actively recruiting participants. Contact the research team at bogas.alexandros@gmail.com for enrollment information.
Where is the NCT07258875 trial being conducted?
This trial is being conducted at Heraklion, Greece.
Who is sponsoring the NCT07258875 clinical trial?
NCT07258875 is sponsored by University of Crete. The principal investigator is Alexandra Papaioannou, Professor of Anaesthesiology at Medical School, University of Crete. The trial plans to enroll 230 participants.