NCT07598552 Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty
| NCT ID | NCT07598552 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Odense University Hospital |
| Condition | Postoperative Cognitive Dysfunction (POCD) |
| Study Type | OBSERVATIONAL |
| Enrollment | 48 participants |
| Start Date | 2026-05-18 |
| Primary Completion | 2026-10-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 48 participants in total. It began in 2026-05-18 with a primary completion date of 2026-10-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to explore early cognitive changes in patients aged 70 years or older undergoing same-day discharge after hip or knee replacement surgery. The main question it aims to answer is: Does patients experience cognitive changes in cognitive test performance from before surgery to the first day after surgery? Participants will: * Complete a cognitive test battery virtually about 14 days before surgery, and on the first and seventh day after their operation. * Record pain levels and pain medicine use during the first week after surgery
Eligibility Criteria
Inclusion Criteria: * Unilateral elective primary Total Hip Arthroplasty, Total Knee Arthroplasty, or Unicompartmental Knee * Native Danish speaker * Spinal anesthesia Exclusion Criteria: * Inability or unwillingness to provide informed consent * Inability to comply with virtual study procedures or follow-up sessions, including because of visual or hearing impairment * Known dementia or other diagnosed cognitive disorders or Brief Assessment of Impaired Cognition (BASIC)≤20 * Parkinson's disease or other neurological conditions causing functional impairment * History of alcohol abuse (≥35 units per week) * Daily use of anxiolytics or hypnotics * Not discharged on the day of surgery
Contact & Investigator
Martin Lindberg-Larsen, Professor
PRINCIPAL INVESTIGATOR
Head of Research / Consultant Orthopaedic Surgeon at Odense University Hospital. Department of Clinical Research, University of Southern Denmark (SDU)
Frequently Asked Questions
Who can join the NCT07598552 clinical trial?
This trial is open to participants of all sexes, aged 70 Years or older, studying Postoperative Cognitive Dysfunction (POCD). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07598552 currently recruiting?
Yes, NCT07598552 is actively recruiting participants. Contact the research team at abdullahi.abdirisak.hirsi2@rsyd.dk for enrollment information.
Where is the NCT07598552 trial being conducted?
This trial is being conducted at Svendborg, Denmark.
Who is sponsoring the NCT07598552 clinical trial?
NCT07598552 is sponsored by Odense University Hospital. The principal investigator is Martin Lindberg-Larsen, Professor at Head of Research / Consultant Orthopaedic Surgeon at Odense University Hospital. Department of Clinical Research, University of Southern Denmark (SDU). The trial plans to enroll 48 participants.