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Recruiting NCT07375667

Dynamic Airway Resistance & ML: Guide Sputum Suction in Ventilated Patients

Trial Parameters

Condition Mechanical Ventilation Pressure High
Sponsor Affiliated Hospital of Nantong University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 258
Sex ALL
Min Age 18 Years
Max Age 90 Years
Start Date 2025-10-30
Completion 2028-12-30
Interventions
The dynamics of airway resistanceconventional suctioning

Brief Summary

Research has shown that timely suctioning not only improves survival rates but also enhances the quality of life in ventilator-dependent patients. However, clinical judgment on the optimal timing for suctioning currently relies primarily on physician experience, lacking scientific evidence \[10\]. Airway viscous resistance reflects the frictional resistance encountered by gas flow within the airways and is closely associated with airway patency. When airway secretions increase, viscous resistance undergoes dynamic changes. Therefore, analyzing these dynamic variations in viscous resistance derived from ventilator waveforms to determine the optimal suctioning timing and assess its clinical impact on the progression of pulmonary inflammation holds significant scientific value and offers new insights and methodologies for clinical practice.

Eligibility Criteria

Inclusion Criteria: * Clinical diagnosis of Acute Respiratory Distress Syndrome (ARDS) * Clinical diagnosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) * Clinical diagnosis of Severe pneumonia Exclusion Criteria: * Clinical diagnosis of multiple organ failure; * Clinical diagnosis of multiple organ bleeding;

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