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Recruiting NCT01950624

NCT01950624 DS-Connect®: The Down Syndrome Registry

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Clinical Trial Summary
NCT ID NCT01950624
Status Recruiting
Phase
Sponsor University of Colorado, Denver
Condition Down Syndrome
Study Type OBSERVATIONAL
Enrollment 100,000 participants
Start Date 2013-09-06
Primary Completion 2035-06

Eligibility & Interventions

Sex All sexes
Min Age N/A
Max Age N/A
Study Type OBSERVATIONAL

Eligibility Fast-Check

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What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 100,000 participants in total. It began in 2013-09-06 with a primary completion date of 2035-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this study is to develop a registry for Down syndrome (DS) to facilitate research participation by individuals with Down syndrome. DS-Connect® is an online survey tool designed to collect demographic data and health information from individuals with DS. It is open to all people with Down syndrome. The purposes of DS-Connect® are: 1. To identify the various phenotypic manifestations of DS. 2. To identify individuals with DS who may be eligible for research studies or new clinical trials, based on specific information about their diagnosis and health history.

Eligibility Criteria

INCLUSION CRITERIA: * Adults (at least 18 years of age) with a diagnosis of DS (including mosaic DS or partial trisomy 21) who are capable of providing consent to participate, or for whom a legally authorized representative (LAR) may give permission on behalf of the individual to participate. Adults with DS who cannot consent for themselves but can provide assent would need to provide assent to their LAR. * Children (up to age 18 years of age) with a diagnosis of DS. Parents/guardians may enter registry information and give permission to participate on behalf of their child; if the child is over 7 years of age and able to provide assent, they must do so. (Note: Once a child has reached age 18, he or she will be prompted to re-enroll into the registry as an adult, if he/she is able to provide informed consent or with the consent of his/her LAR if unable to re-enroll themselves.) No individuals with DS will be excluded from taking part in DS-Connect based on age, race, ethnicity, or gender. EXCLUSION CRITERIA: * A person who does not have a diagnosis of DS (or mosaic DS or partial trisomy 21) * Adults with DS who are not capable of providing informed consent or assent to participate and do not have a Legally Authorized Representative who can do so. In the case where an adults with DS is able to provide assent but does not do so, that adult will be excluded. * A participant, parent, and/or LAR who cannot provide consent or does not read or understand a language that is available for the registry, either English or Spanish. * A child with DS (between the ages of 7 and 18 years) who is capable of providing assent but does not do so. * A child under the age of 18 years whose parents share joint custody and one parent indicates that they do not consent to the child's participation.

Contact & Investigator

Central Contact

Anne Fiala

✉ info@ds-connect.org

📞 (303) 724-6599

Principal Investigator

Joaquin M Espinosa, Ph.D.

PRINCIPAL INVESTIGATOR

Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus

Frequently Asked Questions

Who can join the NCT01950624 clinical trial?

This trial is open to participants of all sexes, studying Down Syndrome. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT01950624 currently recruiting?

Yes, NCT01950624 is actively recruiting participants. Contact the research team at info@ds-connect.org for enrollment information.

Where is the NCT01950624 trial being conducted?

This trial is being conducted at Aurora, United States.

Who is sponsoring the NCT01950624 clinical trial?

NCT01950624 is sponsored by University of Colorado, Denver. The principal investigator is Joaquin M Espinosa, Ph.D. at Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus. The trial plans to enroll 100,000 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology