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Recruiting Phase 4 NCT07088146

Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients

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Trial Parameters

Condition Spinal Anesthesia
Sponsor Rawalpindi Medical College
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 110
Sex FEMALE
Min Age 16 Years
Max Age 40 Years
Start Date 2025-07-20
Completion 2025-10-20
Interventions
DexamethasonePlacebo

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Brief Summary

Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it blocks nerves originating from spinal cord providing both anesthesia and analgesia. This technique avoids harmful exposure of drugs to the baby inside the womb of mother. However this technique provides anesthesia and analgesia of limited duration which can be prolonged by addition of drugs to patient management regimen. One such drug is Dexamethasone which is a steroid commonly administered in the peri-operative period.

Eligibility Criteria

Inclusion Criteria: * American Society of Anesthesiologists (ASA) class: II and above. * Elective Cesarean section under Spinal Anesthesia. Exclusion Criteria: * Gestational diabetes * Body mass index \>35 kg/m2 * Diabetes mellitus * Adrenal insufficiency * Chronically receiving steroids * Allergic to study medications * Sensory block level less than T4

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