Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole Method
Trial Parameters
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Brief Summary
The goal of this clinical trial is to learn if an advanced 256 dry electrode EEG cap augmented with MEG readings and coupled with a new high-resolution fast brain modeling software gives a better EEG and MEG source localization in real time. The main questions it aims to answer are: * Does the testbed better localize brain sources for finger movement? * Does the testbed better localize brain sources for median nerve stimulation? * Does the testbed better localize brain sources for speech processing? * Researchers will compare the predicted cortical locations with MEG data and known anatomical locations of the neuronal generators. Participants will: * Undergo Magnetic Resonance Imaging (MRI) scans for brain and head model creation * Undergo three different EEG tests * Undergo three different MEG tests
Eligibility Criteria
Inclusion Criteria: * Age at least 18 and less than 66 years * Normal hearing and (corrected) vision * Able to understand and give informed consent Exclusion Criteria: * Cardiac pacemaker or pacemaker wires; neurostimulators; implanted pumps * Metal in the body (rods, plates, screws, shrapnel, dentures, IUD) or metallic particles in the eye * Surgical clips in the head or previous neurosurgery * Any magnetic particles in the body * Cochlear implants * Prosthetic heart valves * History of skull injury or defects * Significant claustrophobia; Ménière's disease * Pregnancy, breast feeding * Neurological or psychiatric diagnoses or medications influencing brain function * Current substance abuse (exception: concurrent nicotine use is allowed) * Failure to perform the behavioral tasks or psychological evaluation tests * Prisoners