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Recruiting NCT03862677

NCT03862677 Determining Prognostic Immune Markers in Patients With Ovarian Cancer

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Clinical Trial Summary
NCT ID NCT03862677
Status Recruiting
Phase
Sponsor Leiden University Medical Center
Condition Epithelial Ovarian Cancer
Study Type OBSERVATIONAL
Enrollment 300 participants
Start Date 2020-08-15
Primary Completion 2027-01-31

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
No intervention

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 300 participants in total. It began in 2020-08-15 with a primary completion date of 2027-01-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The IMPRoVE study is a prospective, non-interventional, explorative cohort study to determine prognostic immune markers in patients with epithelial ovarian cancer, fallopian tube cancer, and primary peritoneal cancer (EOC).

Eligibility Criteria

Inclusion Criteria: * Patients with (suspicion of) primary or recurrent EOC with an indication for surgery, chemotherapy and/or immunotherapy. * Age ≥18 years. * WHO performance status 0-2. * Accessible for treatment and follow-up. * Written informed consent. Exclusion Criteria: * Other active malignancy in past 5 years prior to entry into the study, except for treated non-melanoma skin cancer. * Any known severe infection like HIV, hepatitis A, B and C. * Receiving immune suppressive treatment. * Medical or psychological condition which in the opinion of the investigator would not permit the patient to complete the study or sign meaningful informed consent.

Contact & Investigator

Central Contact

Judith R Kroep, MD PhD

✉ j.r.kroep@lumc.nl

📞 +31715263464

Principal Investigator

Judith R Kroep, MD PhD

PRINCIPAL INVESTIGATOR

Leiden University Medical Center

Frequently Asked Questions

Who can join the NCT03862677 clinical trial?

This trial is open to female participants only, aged 18 Years or older, studying Epithelial Ovarian Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03862677 currently recruiting?

Yes, NCT03862677 is actively recruiting participants. Contact the research team at j.r.kroep@lumc.nl for enrollment information.

Where is the NCT03862677 trial being conducted?

This trial is being conducted at Leiden, Netherlands.

Who is sponsoring the NCT03862677 clinical trial?

NCT03862677 is sponsored by Leiden University Medical Center. The principal investigator is Judith R Kroep, MD PhD at Leiden University Medical Center. The trial plans to enroll 300 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology