NCT06469866 Deep Neuromuscular Block Affect the Quality of Recovery After Laparoscopic Hysterectomy
| NCT ID | NCT06469866 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Anqing Municipal Hospital |
| Condition | Neuromuscular Blockade |
| Study Type | INTERVENTIONAL |
| Enrollment | 72 participants |
| Start Date | 2024-06-25 |
| Primary Completion | 2024-11-25 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 72 participants in total. It began in 2024-06-25 with a primary completion date of 2024-11-25.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
BACKGROUND: Some studies have revealed that deep neuromuscular block (NMB) improve surgical conditions and alleviated postoperative pain compared with moderate NMB. The present study investigated deep NMB could improve the quality of recovery after laparoscopic hysterectomy METHODS: seventy-two women with elective laparoscopic hysterectomy were randomly divided into 2 groups: Patients in group A received low-pressure pneumoperitoneum (LPP), which was set at 8-10 mmHg with deep NMB. Patients in group B received standard-pressure pneumoperitoneum (SPP), which was set at 12-14 mmHg with moderate NMB. Primary outcome was the quality of recovery (QoR-15) at 1 day after sugery. The secondary outcomes included postoperative pain, surgical condition, incidence of shoulder pain, the incidence of rescue analgesic drug use, cumulative dose of analgesics, time of first flatus, post-operative nausea and vomiting, time of tracheal tube removal.
Eligibility Criteria
Inclusion Criteria: * American Society of Anesthesiologists (ASA) physical status Ⅰ- Ⅲ * Scheduled for elective laparoscopic hysterectomy Exclusion Criteria: * Inability to give informed consent * BMI \>35 * Renal or hepatic insufficiency * History of preoperative psychiatric * Previous surgery at procedure site * Neuromuscular disease, pregnancy, and contraindications to study medications.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06469866 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 65 Years, studying Neuromuscular Blockade. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06469866 currently recruiting?
Yes, NCT06469866 is actively recruiting participants. Contact the research team at errtg555@163.com for enrollment information.
Where is the NCT06469866 trial being conducted?
This trial is being conducted at Anqing, China.
Who is sponsoring the NCT06469866 clinical trial?
NCT06469866 is sponsored by Anqing Municipal Hospital. The trial plans to enroll 72 participants.