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Recruiting NCT05820802

High Dimensional Analysis of Immune Cells in Pediatric Patients

Trial Parameters

Condition Drug Allergy
Sponsor Seoul National University Hospital
Study Type OBSERVATIONAL
Phase N/A
Enrollment 294
Sex ALL
Min Age 2 Years
Max Age 18 Years
Start Date 2023-04-27
Completion 2026-04-01

Brief Summary

The purpose of this study is to characterize immune cells using single-cell transcriptomic analysis in pediatric patients aged 2 to 18 years undergoing general anesthesia who are expected to receive Rocuronium, a non-depolarizing neuromuscular blocking agent, in the event of an allergic reaction.

Eligibility Criteria

Inclusion Criteria: * Pediatric patients between the ages of 2 and 18 undergoing general anesthesia and surgery using the neuromuscular blocker, rocuronium. Exclusion Criteria: * Patients who have received immunomodulators, immunosuppressants, etc. * Patients with autoimmune diseases (rheumatoid arthritis, lupus, Behcet's disease, etc.) * Patients who regularly take, or have taken within 4 weeks, medications that may affect the immune system (oral steroids, anti-inflammatories, etc.) * Other cases where the Principal Investigator determines that it is difficult to conduct the study.

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