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Recruiting NCT07323940

Correlation Between Perioperative EEG Variability and Postoperative Delirium Incidence.

Trial Parameters

Condition Delirium - Postoperative
Sponsor Xin Chen
Study Type OBSERVATIONAL
Phase N/A
Enrollment 90
Sex ALL
Min Age 65 Years
Max Age N/A
Start Date 2025-12-12
Completion 2026-03-20
Interventions
Collect preoperative and intraoperative electroencephalogram data

Brief Summary

This clinical study aims to investigate whether multiscale entropy analysis of electroencephalogram data can distinguish between ordinary elderly surgical patients and elderly patients with postoperative delirium.This study may help identify postoperative delirium in surgical patients at an early stage.

Eligibility Criteria

Inclusion Criteria: 1. Patients undergoing general anaesthesia with single-lumen endotracheal tube placement; 2. Age ≥65 years, gender unrestricted, body mass index (BMI) 18-28 kg/m²; 3. Normal mouth opening and head/neck mobility; 4. Pre-anaesthesia American Society of Anaesthesiologists (ASA) physical status classification of I or II and Mallampati airway classification of I or II. Exclusion Criteria: 1. Individuals with psychiatric disorders, literacy issues, or communication difficulties who are unable to cooperate with POD screening; 2. Patients with severe lesions in vital organs, such as the heart, lungs, brain, liver or kidneys. 3. Those undergoing cardiac or neurosurgical procedures during this admission; 4. A history of alcohol abuse or recent use of sedatives or opioids; 5. haemoglobin \<100 g/L; 6. Participation in any clinical research studies within the past 3 months.

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