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Recruiting NCT06575712

NCT06575712 Coping Skills Training for Symptom Management and Daily Steps (Step Up)

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Clinical Trial Summary
NCT ID NCT06575712
Status Recruiting
Phase
Sponsor Duke University
Condition Hematopoietic Stem Cell Transplant
Study Type INTERVENTIONAL
Enrollment 177 participants
Start Date 2025-04-21
Primary Completion 2028-08-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 99 Years
Study Type INTERVENTIONAL
Interventions
Step UpUsual Care Plus (UC+)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 177 participants in total. It began in 2025-04-21 with a primary completion date of 2028-08-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim of this study is to test the efficacy of a hybrid in-person and mHealth coping skills training and activity coaching intervention (Step Up), to enable HCT patients to effectively cope with symptoms (pain, fatigue, and stress) to improve their ability to engage in physical activity that can improve physical disability.

Eligibility Criteria

Inclusion Criteria: * receipt of an autologous (auto) HCT or CAR-T cell therapy due to a hematologic malignancy, such as a diagnosis of leukemia, lymphoma, multiple myeloma * age \>18 * self-reported fatigue, pain, and psychological distress (confirmed at recruitment) - minimum two of three symptoms reported at \>3 on 0-10 scale * life expectancy \> 12 months Exclusion Criteria: * cognitive impairment (e.g., dementia) recorded in the chart or suspected by provider * metastases to the brain * presence of a severe psychiatric condition (e.g., psychotic disorder) that would contraindicate safe participation as indicated by the medical chart, treating oncologist, or interactions with the medical/study staff * inability to converse in English

Contact & Investigator

Central Contact

Allison Diachina

✉ allison.diachina@duke.edu

📞 919-416-3421

Frequently Asked Questions

Who can join the NCT06575712 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 99 Years, studying Hematopoietic Stem Cell Transplant. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06575712 currently recruiting?

Yes, NCT06575712 is actively recruiting participants. Contact the research team at allison.diachina@duke.edu for enrollment information.

Where is the NCT06575712 trial being conducted?

This trial is being conducted at Durham, United States.

Who is sponsoring the NCT06575712 clinical trial?

NCT06575712 is sponsored by Duke University. The trial plans to enroll 177 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology