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Recruiting NCT05972343

NCT05972343 COOL-IT-PRO: Cryoablation of Breast Cancer in Non-surgical Patients

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Clinical Trial Summary
NCT ID NCT05972343
Status Recruiting
Phase
Sponsor Washington University School of Medicine
Condition Breast Cancer
Study Type OBSERVATIONAL
Enrollment 100 participants
Start Date 2023-07-26
Primary Completion 2031-07-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Cryoablation

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 100 participants in total. It began in 2023-07-26 with a primary completion date of 2031-07-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This is a subject registry study of patients who undergo cryoablation for their breast cancer after being determined not to be surgical candidates. Data collected as part of this registry will be used to assess the safety of percutaneous ultrasound-guided cryoablation in this population as well as provide long-term follow-up of subjects who received cryoablation.

Eligibility Criteria

Eligibility Criteria: * Diagnosis of breast cancer. * Mass must be visible on ultrasound and \> 5 mm from skin. * Not undergoing surgery, because: * Patient has a medical condition that would not allow sedation or general anesthesia * Surgery is not clinically indicated due to unresectable and/or metastatic disease * Surgery is not clinically indicated for another reason * Patient declines surgery * At least 18 years old. * Able to understand and willing to sign an IRB-approved written informed consent document.

Contact & Investigator

Central Contact

Heather Garrett, M.D.

✉ hvgarrett@wustl.edu

📞 314-454-5206

Principal Investigator

Heather Garrett, M.D.

PRINCIPAL INVESTIGATOR

Washington University School of Medicine

Frequently Asked Questions

Who can join the NCT05972343 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Breast Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05972343 currently recruiting?

Yes, NCT05972343 is actively recruiting participants. Contact the research team at hvgarrett@wustl.edu for enrollment information.

Where is the NCT05972343 trial being conducted?

This trial is being conducted at St Louis, United States.

Who is sponsoring the NCT05972343 clinical trial?

NCT05972343 is sponsored by Washington University School of Medicine. The principal investigator is Heather Garrett, M.D. at Washington University School of Medicine. The trial plans to enroll 100 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology