NCT07253870 Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients
| NCT ID | NCT07253870 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Lahore University of Biological and Applied Sciences |
| Condition | Stroke |
| Study Type | INTERVENTIONAL |
| Enrollment | 54 participants |
| Start Date | 2025-11-20 |
| Primary Completion | 2026-05-20 |
Trial Parameters
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
Brief Summary
This study aims to determine whether transcutaneous vagus nerve stimulation (tVNS) via auricular or cervical branches enhances recovery when combined with task-specific training in subacute stroke patients. We anticipate finding that both stimulation methods may improve upper limb motor function compared to conventional therapy. The research is expected to reveal specific cognitive domains (attention, memory, executive function) that benefit most from each stimulation approach, while also demonstrating meaningful improvements in patients' quality of life measures. These findings may make a significant practical contribution by providing clinicians with evidence-based guidance on suitable tVNS approach for improving functional independence and quality of life for stroke survivors.
Eligibility Criteria
Inclusion Criteria: * First ever ischemic stroke * Subacute phase of stroke 3-6 months post onset * Fugl-Meyer Assessment-Upper Extremity (FMA-UE) scores ranged from 20 - 50 Exclusion Criteria: * Previous injury or surgical intervention of vagus nerve * Patients with cardiac arrest and arrythmias * Uncontrolled hypertension * Apraxia * Other neurologic or musculoskeletal diseases * Presence of implanted electronic devices
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.