NCT07253870 Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients
| NCT ID | NCT07253870 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Lahore University of Biological and Applied Sciences |
| Condition | Stroke |
| Study Type | INTERVENTIONAL |
| Enrollment | 54 participants |
| Start Date | 2025-11-20 |
| Primary Completion | 2026-06-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 54 participants in total. It began in 2025-11-20 with a primary completion date of 2026-06-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to determine whether transcutaneous vagus nerve stimulation (tVNS) via auricular or cervical branches enhances recovery when combined with task-specific training in subacute stroke patients. We anticipate finding that both stimulation methods may improve upper limb motor function compared to conventional therapy. The research is expected to reveal specific cognitive domains (attention, memory, executive function) that benefit most from each stimulation approach, while also demonstrating meaningful improvements in patients' quality of life measures. These findings may make a significant practical contribution by providing clinicians with evidence-based guidance on suitable tVNS approach for improving functional independence and quality of life for stroke survivors.
Eligibility Criteria
Inclusion Criteria: * First ever ischemic stroke * Subacute phase of stroke 3-6 months post onset * Fugl-Meyer Assessment-Upper Extremity (FMA-UE) scores ranged from 20 - 50 Exclusion Criteria: * Previous injury or surgical intervention of vagus nerve * Patients with cardiac arrest and arrythmias * Uncontrolled hypertension * Apraxia * Other neurologic or musculoskeletal diseases * Presence of implanted electronic devices
Contact & Investigator
Aruba Saeed
PRINCIPAL INVESTIGATOR
Lahore University of Biological and Applied Sciences
Frequently Asked Questions
Who can join the NCT07253870 clinical trial?
This trial is open to participants of all sexes, aged 45 Years or older, up to 70 Years, studying Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07253870 currently recruiting?
Yes, NCT07253870 is actively recruiting participants. Contact the research team at wafamalik583@gmail.com for enrollment information.
Where is the NCT07253870 trial being conducted?
This trial is being conducted at Lahore, Pakistan.
Who is sponsoring the NCT07253870 clinical trial?
NCT07253870 is sponsored by Lahore University of Biological and Applied Sciences. The principal investigator is Aruba Saeed at Lahore University of Biological and Applied Sciences. The trial plans to enroll 54 participants.
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