NCT07375121 Comparison of the Efficacy and Safety of Fixed-rate Basal Infusion Mode and Time-programmed Decremental Background Infusion Mode of Intravenous PCA Following Mixed Surgery
| NCT ID | NCT07375121 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Beijing Tiantan Hospital |
| Condition | Surgery |
| Study Type | INTERVENTIONAL |
| Enrollment | 450 participants |
| Start Date | 2025-12-30 |
| Primary Completion | 2026-10-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 450 participants in total. It began in 2025-12-30 with a primary completion date of 2026-10-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Perioperative pain management affects patient recovery. However, the rate of moderate to severe postoperative pain is as high as 73.8%, which hinders recovery and increases the risk of complications. Although opioids are the first-line analgesics, excessive use leads to adverse reactions. The traditional fixed-rate PCA mode is difficult to match the changes in postoperative pain. This study will compare different PCA mode optimization strategies, assuming that they can reduce opioid dosage, improve analgesic effect, and reduce adverse reactions, providing high-quality evidence-based basis for postoperative analgesia and promoting individualized and intelligent management.
Eligibility Criteria
Inclusion Criteria: * aged between 18 to 65 years; * American Society of Anesthesiologists physical status Ⅰ - Ⅲ; * Patients scheduled for elective mixed surgery were enrolled. Mixed surgeries included thoracoscopic surgery, laparoscopic surgery, hysteroscopy surgery, laparotomy, thoracotomy, open spinal surgery, craniotomy, and so on. Exclusion Criteria: * Chronic pain syndromes; * Psychiatric disorders; * Severe cardiovascular or cerebrovascular disease, renal or hepatic functional dysfunction, or allergic to PCA medications.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07375121 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Surgery. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07375121 currently recruiting?
Yes, NCT07375121 is actively recruiting participants. Contact the research team at 13611326978@163.com for enrollment information.
Where is the NCT07375121 trial being conducted?
This trial is being conducted at Beijing, China.
Who is sponsoring the NCT07375121 clinical trial?
NCT07375121 is sponsored by Beijing Tiantan Hospital. The trial plans to enroll 450 participants.