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pain management

Total Trials
15
Recruiting Now
15
Trial Phases
Phase 4

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — pain management Clinical Trials

How many clinical trials are currently recruiting for pain management?
ClinicalMetric currently tracks 15 actively recruiting clinical trials for pain management, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 15. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for pain management?
pain management research spans Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a pain management clinical trial?
Eligibility criteria for pain management trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 4
1
Top Sponsors
Ankara Etlik City Hospital 2 trials
Beijing Tiantan Hospital 2 trials
New Valley University 1 trial
Tel-Aviv Sourasky Medical Center 1 trial
Istinye University 1 trial

Recruiting Clinical Trials

NCT06406712
Recruiting
Retroclavicular Block in Vascular Surgey
Enrollment
80 pts
Location
Egypt
Sponsor
New Valley University
View Trial →
NCT06966869
Recruiting
Evaluation of Fentanyl Transdermal Patch Absorption in Hemodynamically Unstable ICU Patients.
Enrollment
40 pts
Location
Israel
Sponsor
Tel-Aviv Sourasky Medical Cent...
View Trial →
NCT07745972
Recruiting
Ultrasound-Guided Recto-Intercostal Fascial Plane Block in Laparoscopic Cholecystectomy
Enrollment
60 pts
Location
Turkey (Türkiye)
Sponsor
Istinye University
View Trial →
NCT07716540
Recruiting
Analgesic Efficacy of Ultrasound-Guided Deep Iliacus Plane Block in Patients Undergoing Hip Fracture Surgery
Enrollment
52 pts
Location
Turkey (Türkiye)
Sponsor
Kanuni Sultan Suleyman Trainin...
View Trial →
NCT07158476 Phase 4
Recruiting
Efficacy of Methylprednisolone for Pain Control After ACL Repair
Enrollment
90 pts
Location
United States
Sponsor
St. Louis University
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NCT07824908
Recruiting
Effect Of Specimen Extraction Site And Local Anesthesia On Postoperative Pain In Laparoscopic Appendectomy
Enrollment
300 pts
Location
Turkey (Türkiye)
Sponsor
YUNUS YÜKSEL
View Trial →
NCT06953752
Recruiting
Effects of Music During Atrial Fibrillation Ablation Under Conscious Sedation
Enrollment
120 pts
Location
China
Sponsor
Shaoxing People's Hospital
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NCT07151443
Recruiting
Comparison of Conventional and Retroclavicular Approaches for Ultrasound-guided Infraclavicular Brachial Plexus Block
Enrollment
60 pts
Location
Turkey (Türkiye)
Sponsor
Ankara Etlik City Hospital
View Trial →
NCT07123740
Recruiting
Comparison of the Postoperative Analgesic Effects of ITM and Bi-level ESPB in Liver Transplantation Donors
Enrollment
60 pts
Location
Turkey (Türkiye)
Sponsor
Ankara Etlik City Hospital
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NCT06696573
Recruiting
Effectiveness of Anti-Inflammatory Drugs for Preventing Pain Versus Treating Pain During Medical Abortion From 13 to 22 Weeks at Hung Vuong Hospital
Enrollment
180 pts
Location
Vietnam
Sponsor
Le Thi Kieu Trang
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NCT06664203
Recruiting
Efficacy of Variable Volume Truncal Blocks in Upper Limb Orthopedic Surgery
Enrollment
60 pts
Location
Turkey (Türkiye)
Sponsor
Gaziosmanpasa Research and Edu...
View Trial →
NCT07442539
Recruiting
The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Hemorrhoid Surgery
Enrollment
156 pts
Location
China
Sponsor
Beijing Tiantan Hospital
View Trial →
NCT07524049
Recruiting
Giving Children a Voice in Paediatric Anaesthesia
Enrollment
1,040 pts
Location
Switzerland
Sponsor
Insel Gruppe AG, University Ho...
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NCT07872670
Recruiting
Virtual Reality Therapy to Improve Arthroplasty Outcomes
Enrollment
40 pts
Location
United Kingdom
Sponsor
NHS Highland Research, Develop...
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NCT07432711
Recruiting
The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Video-assisted Thoracoscopic Surgery
Enrollment
100 pts
Location
China
Sponsor
Beijing Tiantan Hospital
View Trial →

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology