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pain management

Total Trials
9
Recruiting Now
9
Trial Phases
Various

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — pain management Clinical Trials

How many clinical trials are currently recruiting for pain management?
ClinicalMetric currently tracks 9 actively recruiting clinical trials for pain management, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 9. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for pain management?
pain management research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a pain management clinical trial?
Eligibility criteria for pain management trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 1 trial
Ankara Yildirim Beyazıt University 1 trial
Albert Einstein College of Medicine 1 trial
Eskisehir Osmangazi University 1 trial
Lviv National Medical University 1 trial

Recruiting Clinical Trials

NCT04990713
Recruiting
QoR40 Between Intercostal Block and Intercostal Block and Serratus Plane Catheter During VATS
Enrollment
200 pts
Location
Canada
Sponsor
London Health Sciences Centre ...
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NCT07067580
Recruiting
Effect of Breathing Exercise on Pain and Quality of Recovery in After Transplantation Patients: A Randomized Controlled Trial
Enrollment
60 pts
Location
Turkey (Türkiye)
Sponsor
Ankara Yildirim Beyazıt Univer...
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NCT07032766
Recruiting
Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures
Enrollment
220 pts
Location
United States
Sponsor
Albert Einstein College of Med...
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NCT07642674
Recruiting
The Effect of Intravenous Dexketoprofen on the Severity and Incidence of Rebound Pain
Enrollment
66 pts
Location
Turkey (Türkiye)
Sponsor
Eskisehir Osmangazi University
View Trial →
NCT07380789
Recruiting
Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine
Enrollment
50 pts
Location
Ukraine
Sponsor
Lviv National Medical Universi...
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NCT07197710
Recruiting
Imagined Acupuncture for Postoperative Pain After Spinal Surgery
Enrollment
120 pts
Location
United States
Sponsor
Jingping Wang, MD, Ph.D.
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NCT07011472
Recruiting
Post-Operative Analgesic Selection in Patients Planned for Third Molar Extraction After Undergoing Shared Decision Making Using 2- Versus 3-Option Decision-Aids
Enrollment
100 pts
Location
United States
Sponsor
Rutgers, The State University ...
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NCT06785389
Recruiting
Influence of Preoperative Fear on Pain and Postoperative Outcomes
Enrollment
138 pts
Location
Spain
Sponsor
Hospital Universitario de Gran...
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NCT06488183
Recruiting
Laparoscopic Preperitoneal Local Anesthetic Infiltration Versus Ultrasound Guided Quadratus Lumborum Block in Laparoscopic Bariatric Surgery
Enrollment
44 pts
Location
Egypt
Sponsor
sarah mohamed
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Related Conditions

video assisted thoracic surgery vats (1) transplantation (1) quality of recovery 40 (1) rib fracture multiple (1) serratus anterior plane block (1) postoperative pain (1) rebound pain (1) interscalene block (1) thoracic trauma (1) pulmonary function (1) quality of life (1) functional outcome (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology