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Recruiting NCT06514365

NCT06514365 Comparison of the Analgesic Effect of Subsartorial Saphenous Block and Popliteal Sciatic vs Subsartorial Saphenous Block and IPACK in Total Knee Replacement Surgery.

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Clinical Trial Summary
NCT ID NCT06514365
Status Recruiting
Phase
Sponsor Germans Trias i Pujol Hospital
Condition Pain, Acute
Study Type INTERVENTIONAL
Enrollment 62 participants
Start Date 2020-06-10
Primary Completion 2024-06-01

Eligibility & Interventions

Sex Female only
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
IPACK block with Bupivacaine 0.25% with adrenaline

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 62 participants in total. It began in 2020-06-10 with a primary completion date of 2024-06-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Total knee replacement surgery is associated with significant pain in the immediate postoperative period, especially in movement. In turn, this is associated with more subsequent chronic pain. There are multiple options and the tendency is to perform increasingly distal nerve blocks to minimize limb weakness and thus allow early rehabilitation. In 2012, in an oral communication, Sanjay Sinha described a new nerve block called iPACK ("Interspace between the Popliteal Artery and the Capsule of the posterior Knee"). There are few studies on the efficacy of such a blockade so far, but none comparing the groups saphene + sciatic blocks vs. saphene + iPACK blocks. Therefore, this study aims to provide more information on the effectiveness this nerve blocks, in total knee replacement, in terms of analgesia and motor function.

Eligibility Criteria

Inclusion Criteria: * Patients with osteoarthritis scheduled for total primary knee arthroplasty with same surgeons * Locoregional anesthesia * Age equal to or greater than 18 years * Consent to participate in the study Exclusion Criteria: * Age under 18 years old * General anesthesia * Allergy to local anesthetics * Severe kidney failure (Cr ≥ 2mg / dL) * Chronic opioid use (over 3 months) * Chronic pregabalin / gabapentin use (more than 3 months) * Psychiatric illness that may interfere with the evaluation or follow-up

Contact & Investigator

Central Contact

Madalina Dinu, Mrs

✉ madidinu@hotmail.com

📞 0034600349517

Frequently Asked Questions

Who can join the NCT06514365 clinical trial?

This trial is open to female participants only, aged 18 Years or older, studying Pain, Acute. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06514365 currently recruiting?

Yes, NCT06514365 is actively recruiting participants. Contact the research team at madidinu@hotmail.com for enrollment information.

Where is the NCT06514365 trial being conducted?

This trial is being conducted at Badalona, Spain.

Who is sponsoring the NCT06514365 clinical trial?

NCT06514365 is sponsored by Germans Trias i Pujol Hospital. The trial plans to enroll 62 participants.

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