NCT06009588 Comparison of Self- and Balloon-expandable Valves in Patients With Ascending Aortic Dilation Undergoing Transcatheter Aortic Valve Replacement: The AAD-CHOICE
| NCT ID | NCT06009588 |
| Status | Recruiting |
| Phase | — |
| Sponsor | China National Center for Cardiovascular Diseases |
| Condition | Aortic Stenosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2023-08-31 |
| Primary Completion | 2026-08-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2023-08-31 with a primary completion date of 2026-08-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aimed at comparing the performance of self-expandable valves versus balloon-expandable valves in patients with ascending aortic dilation undergoing transcatheter aortic valve replacement.
Eligibility Criteria
Inclusion Criteria: * Severe aortic stenosis; * Transfemoral access; * Preoperative aortic CT suggesting maximum ascending aortic diameter ≥45mm and \<55mm; * Anticipated life expectancy \>1 year; * Age ≥ 65 years. Exclusion Criteria: * Dominant aortic regurgitation,; * A history of SAVR or TAVR; * A history of aortic surgery; * Emergent TAVR.
Contact & Investigator
Xiangbin Pan, MD
PRINCIPAL INVESTIGATOR
Department of Structural Heart Disease, National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Frequently Asked Questions
Who can join the NCT06009588 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, studying Aortic Stenosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06009588 currently recruiting?
Yes, NCT06009588 is actively recruiting participants. Contact the research team at ankang913@126.com for enrollment information.
Where is the NCT06009588 trial being conducted?
This trial is being conducted at Beijing, China.
Who is sponsoring the NCT06009588 clinical trial?
NCT06009588 is sponsored by China National Center for Cardiovascular Diseases. The principal investigator is Xiangbin Pan, MD at Department of Structural Heart Disease, National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College. The trial plans to enroll 100 participants.