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Medical Condition
aortic stenosis
Total Trials
14
Recruiting Now
14
Trial Phases
EARLY_Phase 1, Phase 4, Phase 3
ClinicalMetric tracks all active clinical trials for aortic stenosis sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.
Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.
Frequently Asked Questions — aortic stenosis Clinical Trials
How many clinical trials are currently recruiting for aortic stenosis?
ClinicalMetric currently tracks 14 actively recruiting clinical trials for aortic stenosis, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 14. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for aortic stenosis?
aortic stenosis research spans Phase 1 (1 trial), Phase 3 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a aortic stenosis clinical trial?
Eligibility criteria for aortic stenosis trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1 1
Phase 3 1
Phase 4 1
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT05629104
Recruiting
Prediction of Long-term Outcome in Aortic Stenosis After Valve Intervention
Enrollment
300 pts
Location
Sweden
Sponsor
Uppsala University
NCT05235555
Recruiting
EffecTAVI Registry
Enrollment
1,000 pts
Location
Italy
Sponsor
Federico II University
NCT07201363
Recruiting
Biomarkers of Inflammation and Fibrosis in Conduction Disorders After TAVI
Enrollment
102 pts
Location
Croatia
Sponsor
Clinical Hospital Center Rijek...
NCT06777368
Recruiting
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
Enrollment
225 pts
Location
United States
Sponsor
Medtronic Cardiovascular
NCT07205068
Recruiting
Improved Outcomes With Pre-Procedure Shockwave IVL of Common Femoral Artery Access Site Prior to Large Bore Access and Pre-Closure
Enrollment
100 pts
Location
United States
Sponsor
University of Tennessee Gradua...
NCT02856620
Recruiting
The Role of Cardiac Mechanics, Biomarkers and Frailty in Aortic Stenosis
Enrollment
450 pts
Location
Canada
Sponsor
Christine Henri
NCT05866640 EARLY_Phase 1
Recruiting
Feasibility Trial of the F2 Filter and Delivery System for Embolic Protection During TAVR
Enrollment
10 pts
Location
Georgia
Sponsor
EnCompass Technologies, Inc.
NCT06007222 Phase 4
Recruiting
Non-antithrombotic Therapy After Transcatheter Aortic Valve Implantation Trial
Enrollment
400 pts
Location
Japan
Sponsor
OCEAN-SHD Study Group
NCT04126018
Recruiting
Comparative Imaging Assessment of Valvular Heart Disease
Enrollment
200 pts
Location
United States
Sponsor
The Cleveland Clinic
NCT04968509 Phase 3
Recruiting
Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis
Enrollment
160 pts
Location
China
Sponsor
Beijing Anzhen Hospital
NCT07479992
Recruiting
Multicenter Study for the Validation of Willem AI: Aortic StenoSis Early Diagnosis With AI-electrocardiogram Study
Enrollment
5,000 pts
Location
Germany
Sponsor
Idoven 1903 S.L.
NCT06991517
Recruiting
A Study of Transcatheter Aortic Valve Replacement Case Selection and Valve Sizing Using the ABC Bicuspid Sizing Algorithm
Enrollment
290 pts
Location
Australia, Canada, C...
Sponsor
World Health Research Inc.
NCT06722066
Recruiting
Impact of Aortic Annulus Calcification on Long-Term Outcomes Following Transcatheter Aortic Valve Replacement: SAINT-TAVR Calcium Registry
Enrollment
500 pts
Location
South Korea
Sponsor
Eunpyeong St. Mary's Hospital
NCT07052071
Recruiting
Impact of Transcatheter Aortic Valve Implantation (TAVI) on the Gut Microbiota in Patients With Aortic Valve Stenosis
Enrollment
40 pts
Location
Greece
Sponsor
Hippocration General Hospital
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology