Cold and Heat Investigation to Lower Levels of Depression
Trial Parameters
Brief Summary
This study will recruit 112 medically healthy adults (aged 18-65) currently experiencing depressive symptoms to be randomized to receive either a single Whole Body Hyperthermia (heat therapy) treatment or a Whole Body Hyperthermia treatment followed by a cold water plunge. Participants will complete a baseline assessment of their depressive symptoms as well as 1-week and 2-week post-treatment followup assessments.
Eligibility Criteria
Inclusion Criteria: * Individuals who currently meet study criteria for depression or individuals who do not currently meet criteria for depression * English or Spanish speaking (able to provide informed consent and complete questionnaires in one of these languages) * Able and willing to adhere to trial requirements, including attending all trial visits, preparatory and follow-up sessions, and completing all trial evaluations. Exclusion Criteria: * Previous adverse reaction to hypothermia, hyperthermia and/or infrared exposure * Use of any medication that may impact thermoregulatory capacity. * Pregnancy, active lactation, or intention to become pregnant during the study period. * Endorses current active suicidal ideation with a plan or made a suicide attempt in the prior 6 months.