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Recruiting NCT06725836

Clinical Testing of Invasive Spinal Cord Stimulation and Evaluation of Its Physiological Effects Using the Electroencephalography

Trial Parameters

Condition Spinal Cord Injuries (SCI)
Sponsor Artur Biktimirov
Study Type INTERVENTIONAL
Phase N/A
Enrollment 35
Sex ALL
Min Age N/A
Max Age N/A
Start Date 2023-04-22
Completion 2028-12
Interventions
Implantation of electrodes into the epidural space for spinal cord stimulationSelection of the optimal spinal cord stimulation program for spastic syndrome suppressionSelection of the optimal spinal cord stimulation program for volitional motor control

Brief Summary

The aim of the study is to identify the specific characteristics of brain network dysfunctions and assess the recovery of their functionality through the recording of resting-state electroencephalography (EEG) during rehabilitation using spinal cord stimulation (SCS). Researchers expect that effective SCS scenarios will result in progressive alterations in the quantitative metrics of resting-state EEG throughout the rehabilitation period. The data obtained may be used to optimize rehabilitation protocols and develop personalized approaches for recovery after spinal cord injury.

Eligibility Criteria

Inclusion Criteria: * Patients with implanted spinal cord stimulation device * Patients undergoing a scheduled implantation of a spinal cord stimulation device * Complete spinal cord injury * Incomplete spinal cord injury Exclusion Criteria: * Presence of severe somatic pathology that prevents surgical treatment and participation in the study * Presence of mental disorders, severe depression, or a history of suicidal tendencies * History of oncology * History of epilepsy * History of stroke * Inability to perform electrical stimulation due to other somatic pathology * Purulent-septic pathology * Drug addiction (including in the medical history) * Central nervous system developmental anomalies * Any conditions that, in the investigator's opinion, meet the exclusion criteria

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