NCT07536204 Characterization of JAK1 and JAK2 Activation in Gingival Tissues During Homeostasis and Periodontitis
| NCT ID | NCT07536204 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Chile |
| Condition | Periodontitis |
| Study Type | OBSERVATIONAL |
| Enrollment | 30 participants |
| Start Date | 2023-06-01 |
| Primary Completion | 2027-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 30 participants in total. It began in 2023-06-01 with a primary completion date of 2027-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to examine JAK1/2 pathway activation in gingival tissues from adults with healthy gingiva and those with inflamed gingiva (periodontitis). The main question it aims to answer is: Is the JAK1/2 pathway overactivated in periodontitis compared to health? Participants with healthy gingiva and periodontitis will donate gingival tissue to study the JAK1/2 pathway. All participants wil receive diagnosis and treatment of the gingival condition.
Eligibility Criteria
Inclusion Criteria: * Adults * Sistemically healthy Exclusion Criteria: * Active Maliganancy * History of radiation to the head-neck region * Chemotherapy or radiation within the last 5 years * History of hepatitis B/C or HIV infection * Autoimmune diseases * Diagnosis of diabetes * Pregnancy or lactation * More than 3 hospitalizations over the last 3 years * Use of systemic antibiotics over the last 3 months * Use of systemic corticosteroids or immunosuppressants over the last 3 months * Use of cytokine therapy over the last 3 months * Use of large doses of pre/probiotic supplements over the last 3 months * Smoke more than 10 cigarettes per day
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07536204 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Periodontitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07536204 currently recruiting?
Yes, NCT07536204 is actively recruiting participants. Contact the research team at ndutzan@uchile.cl for enrollment information.
Where is the NCT07536204 trial being conducted?
This trial is being conducted at Santiago, Chile.
Who is sponsoring the NCT07536204 clinical trial?
NCT07536204 is sponsored by University of Chile. The trial plans to enroll 30 participants.