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Recruiting NCT05026554

NCT05026554 Characterization of Chronic Hand Eczema

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Clinical Trial Summary
NCT ID NCT05026554
Status Recruiting
Phase
Sponsor Dr. Robert Bissonnette
Condition Chronic Hand Eczema
Study Type OBSERVATIONAL
Enrollment 270 participants
Start Date 2021-06-30
Primary Completion 2027-06-30

Trial Parameters

Condition Chronic Hand Eczema
Sponsor Dr. Robert Bissonnette
Study Type OBSERVATIONAL
Phase N/A
Enrollment 270
Sex ALL
Min Age 18 Years
Max Age 65 Years
Start Date 2021-06-30
Completion 2027-06-30
Interventions
Tape stripping

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Brief Summary

Prospective longitudinal study to characterize Choronic Hand Eczema (CHE) subtypes and Atopic Dermatitis (AD) with noninvasive molecular and imaging techniques, and assess changes through time and its association with quality of life.

Eligibility Criteria

Inclusion Criteria: All subjects: 1. Male or female subjects aged 18 to 65 years, inclusive, at the time of consent. 2. Subject is willing to participate and is capable of giving informed consent. Note: Consent must be obtained prior to any study-related procedures. 3. Subject must be willing to comply with all study procedures and must be available for the duration of the study. CHE subjects only: 4. Subject has at least a 6-month history of CHE before Screening (information obtained from medical chart or subject's physician, or directly from the subject). 5. Subject has moderate to severe CHE as defined by an IGA score of ≥3 at Screening and Day 1. 6. Subject has CHE covering ≥0.25% of BSA on palmar surface of hands at Screening and Day 1. 7. Subjects has CHE that can be categorized in one of the following CHE subtypes at Day 1: * Atopic hand eczema (without wet-work or excessive contact with irritants) * Irritant contact hand eczema without atopic disease * Hyperkeratotic hand eczem

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