NCT05634733 Change in MAPSE During Treatment of Sepsis
| NCT ID | NCT05634733 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Maryland, Baltimore |
| Condition | Sepsis |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2023-04-01 |
| Primary Completion | 2030-04-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2023-04-01 with a primary completion date of 2030-04-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisting heart problems. Factors related to the infection may cause the heart to not pump as well as it should, causing critical illness in the form of low blood pressure (shock) and heart failure. Ultrasound is frequently used in the emergency department to evaluate why a patient might have low blood pressure. Part of that evaluation may include obtaining ultrasound images and making measurements about how well or poorly the heart is pumping. The investigators will evaluate a certain measurement that relates to cardiac function, determine how it changes in patients before and after they are treated for septic shock. This will involve placing an ultrasound probe on the patient's chest, measuring the upward and downward movement of the mitral valve, the mitral annulus systolic plane excursion (MAPSE), and comparing the measurements before and after treatment is started. The investigators are attempting to determine if this measurement improves before and after treatment.
Eligibility Criteria
Inclusion Criteria: * Diagnosis of Sepsis or Septic Shock Exclusion Criteria: * Age equal to or less than 17 * patient in the emergency department * Unable to perform POCUS exam due to medical necessity * Patients without sepsis * unable to obtain consent or have a legal representative consent
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05634733 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Sepsis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05634733 currently recruiting?
Yes, NCT05634733 is actively recruiting participants. Contact the research team at alexis.salerno@som.umaryland.edu for enrollment information.
Where is the NCT05634733 trial being conducted?
This trial is being conducted at Baltimore, United States.
Who is sponsoring the NCT05634733 clinical trial?
NCT05634733 is sponsored by University of Maryland, Baltimore. The trial plans to enroll 50 participants.