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Recruiting NCT07478146

NCT07478146 Brief Title: Aerobic Training on Cerebrovascular Function, Cognition and Gait in Parkinson's Disease

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Clinical Trial Summary
NCT ID NCT07478146
Status Recruiting
Phase —
Sponsor Raphael Mendes Ritti Dias
Condition PARKINSON DISEASE (Disorder)
Study Type INTERVENTIONAL
Enrollment 40 participants
Start Date 2026-02-28
Primary Completion 2027-06-30

Eligibility & Interventions

Sex All sexes
Min Age 40 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Aerobic trainingUsual Care

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 40 participants in total. It began in 2026-02-28 with a primary completion date of 2027-06-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This randomized controlled trial will investigate the effects of a 12-week supervised aerobic training program on cerebrovascular function, peripheral vascular health, cardiovascular autonomic modulation, cognition, non-motor symptoms, sleep, mood, gait biomechanics, quality of life, and body composition in patients with Parkinson's disease (Hoehn \& Yahr stages 1-3). Participants will be randomly allocated to aerobic training or usual care.

Eligibility Criteria

Inclusion Criteria: * Clinical diagnosis of Parkinson's disease * Hoehn \& Yahr stages 1-3 * Stable antiparkinsonian medication for at least 4 weeks * Montreal Cognitive Assessment (MoCA) score ≥ 18 * Ability to walk independently (with or without assistive device) * Medical clearance for participation in moderate-intensity exercise Exclusion Criteria: * Change in medication * Contraindication to exercise

Contact & Investigator

Central Contact

Raphael M Ritti-Dias, PhD

✉ raphaelritti@gmail.com

📞 +5519999406878

Principal Investigator

Raphael M Ritti-Dias, PhD

PRINCIPAL INVESTIGATOR

University of Nove de Julho

Frequently Asked Questions

Who can join the NCT07478146 clinical trial?

This trial is open to participants of all sexes, aged 40 Years or older, studying PARKINSON DISEASE (Disorder). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07478146 currently recruiting?

Yes, NCT07478146 is actively recruiting participants. Contact the research team at raphaelritti@gmail.com for enrollment information.

Where is the NCT07478146 trial being conducted?

This trial is being conducted at São Paulo, Brazil.

Who is sponsoring the NCT07478146 clinical trial?

NCT07478146 is sponsored by Raphael Mendes Ritti Dias. The principal investigator is Raphael M Ritti-Dias, PhD at University of Nove de Julho. The trial plans to enroll 40 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology