NCT05860803 Breathing Training and Exercise Capacity in Non-CFB
| NCT ID | NCT05860803 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mayo Clinic |
| Condition | Non-cystic Fibrosis Bronchiectasis |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-01-15 |
| Primary Completion | 2026-12-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2024-01-15 with a primary completion date of 2026-12-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this research is to investigate whether a home-based and health coach supported specific breathing and respiratory muscle training program improves the ability to exercise, the function of the lungs and breathing muscles, and general clinical status in people with non-cystic fibrosis bronchiectasis (non-CFB).
Eligibility Criteria
Inclusion Criteria: * Mayo Clinic patient with confirmed diagnosis of Non-Cystic Fibrosis Bronchiectasis (non-CFB): Non-CFB as confirmed by clinical history, including cough, shortness of breath, exertional dyspnea, pulmonary function tests, and high-resolution computed tomography. Patients will be considered clinically stable if there is no evidence of an exacerbation or change(s) in medical therapy in the previous three weeks. * Able and willing to provide informed consent to participate in the study. Exclusion Criteria: * Presence of significant coexisting disease, neurological conditions, and/or orthopedic complications that affect ability to undertake exercise. * Presence of advanced heart failure. * Current use of antibiotics. * Acute exacerbation(s) within 3-weeks prior to study commencement. * Participation within a pulmonary rehabilitation program within 6-months prior to study commencement.
Contact & Investigator
Bryan Taylor, PhD
PRINCIPAL INVESTIGATOR
Mayo Clinic
Frequently Asked Questions
Who can join the NCT05860803 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 80 Years, studying Non-cystic Fibrosis Bronchiectasis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05860803 currently recruiting?
Yes, NCT05860803 is actively recruiting participants. Visit ClinicalTrials.gov or contact Mayo Clinic to inquire about joining.
Where is the NCT05860803 trial being conducted?
This trial is being conducted at Jacksonville, United States.
Who is sponsoring the NCT05860803 clinical trial?
NCT05860803 is sponsored by Mayo Clinic. The principal investigator is Bryan Taylor, PhD at Mayo Clinic. The trial plans to enroll 50 participants.