← Back to Clinical Trials
Recruiting NCT05963451

NCT05963451 Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT05963451
Status Recruiting
Phase
Sponsor Université de Sherbrooke
Condition Chronic Low-back Pain
Study Type OBSERVATIONAL
Enrollment 80 participants
Start Date 2023-09-07
Primary Completion 2027-07-16

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 75 Years
Study Type OBSERVATIONAL
Interventions
No intervention

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 80 participants in total. It began in 2023-09-07 with a primary completion date of 2027-07-16.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The goal of this observational study is to better understand the role of the brain in chronic low back pain patients.

Eligibility Criteria

Inclusion Criteria: * Low back pain (≥ 6 months) with or without pain radiating to the legs or radiating to the neck * Positive medial branch blocks, suggesting that the pain originates from the lumbar facet joints * Average pain intensity of ≥ 3/10 in the 24-hour period before the initial visit * Pain primarily localized in the lower back Exclusion Criteria: * Inadequate pain relief or relief of less than three months following selective thermoablation of medial lumbar branches by radiofrequency * Neurological, cardiovascular, or pulmonary disorders * Comorbid pain syndrome * History of surgical intervention in the back * A corticosteroid infiltration within the past year * Pregnancy (current or planned during the course of the study) * Contra-indication to Magnetic Resonance Imaging (MRI)

Contact & Investigator

Central Contact

Pascal Tétreault, PhD

✉ pascal.tetreault@usherbrooke.ca

📞 819-346-1110

Frequently Asked Questions

Who can join the NCT05963451 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Chronic Low-back Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05963451 currently recruiting?

Yes, NCT05963451 is actively recruiting participants. Contact the research team at pascal.tetreault@usherbrooke.ca for enrollment information.

Where is the NCT05963451 trial being conducted?

This trial is being conducted at Sherbrooke, Canada.

Who is sponsoring the NCT05963451 clinical trial?

NCT05963451 is sponsored by Université de Sherbrooke. The trial plans to enroll 80 participants.

Related Trials

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology