NCT07578675 Brain Cognitive Network Abnormalities in Anemia Patients Using fNIRS
| NCT ID | NCT07578675 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Institute of Hematology & Blood Diseases Hospital, China |
| Condition | Aplastic Anemia |
| Study Type | OBSERVATIONAL |
| Enrollment | 323 participants |
| Start Date | 2025-10-11 |
| Primary Completion | 2028-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 323 participants in total. It began in 2025-10-11 with a primary completion date of 2028-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Anemia is a global public health concern and is closely linked to dysfunction of brain cognitive neural networks, a key mechanism underlying cognitive impairment. Such deficits-including declines in memory, learning, processing speed, and executive function-reduce daily living abilities and increase risks of falls and depression. Functional near-infrared spectroscopy (fNIRS) enables real-time monitoring of oxygenated and deoxygenated hemoglobin fluctuations, reflecting brain network function. This study aims to identify affected neural network regions in anemic patients and visualize connectivity changes using heatmaps and arc-based mapping. The findings will support early detection of cognitive impairment and guide precise clinical interventions, ultimately informing individualized treatment strategies to enhance therapeutic outcomes and quality of life.
Eligibility Criteria
Inclusion Criteria: * Diagnosis of anemia * First hospitalization * Male or female, aged 18-65 years * Willing and able to comply with the requirements for this study and written informed consent Exclusion Criteria: * History of psychiatric illness * History of severe brain disease * Subjects that the investigator believes have other reasons that make them unsuitable for inclusion in this study
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07578675 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Aplastic Anemia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07578675 currently recruiting?
Yes, NCT07578675 is actively recruiting participants. Contact the research team at kuangzhexiang@ihcams.ac.cn for enrollment information.
Where is the NCT07578675 trial being conducted?
This trial is being conducted at Tianjin, China.
Who is sponsoring the NCT07578675 clinical trial?
NCT07578675 is sponsored by Institute of Hematology & Blood Diseases Hospital, China. The trial plans to enroll 323 participants.