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Recruiting NCT06861868

NCT06861868 Brain and Behavior Influences on Obesity Development From Infancy Through Childhood

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Clinical Trial Summary
NCT ID NCT06861868
Status Recruiting
Phase
Sponsor Johns Hopkins University
Condition Obesity and Overweight
Study Type INTERVENTIONAL
Enrollment 210 participants
Start Date 2024-12-02
Primary Completion 2029-03-31

Eligibility & Interventions

Sex All sexes
Min Age 7 Years
Max Age 12 Years
Study Type INTERVENTIONAL
Interventions
fMRI cue reactivity taskfMRI go no go taskAd libitum meal test

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 210 participants in total. It began in 2024-12-02 with a primary completion date of 2029-03-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function. This data is collected in a sub-sample of RESONANCE, a large study of families of children from infancy through childhood. The results will lay foundations for the development of early interventions to prevent or treat obesity.

Eligibility Criteria

Inclusion Criteria: * Participants from the RESONANCE cohort are eligible if the participant will reach 7-12 years of age during the proposed project period and have no food allergies. Exclusion Criteria: * Exclusion criteria for RESONANCE include: 1. In utero exposure to alcohol, cigarette, or illicit substances; 2. First trimester fetal US abnormalities; 3. Complicated pregnancy (e.g., pre-eclampsia); 4. Complicated delivery, including APGAR scores less than 8 and/or neonatal intensive care unit (NICU) admission; 5. History of neurological (e.g., epilepsy), psychiatric (e.g., anxiety or depression requiring treatment with medication) or developmental disorder (e.g., autism spectrum disorder (ASD), dyslexia); 6. Contraindications for MRI including metal in the body, claustrophobia.

Contact & Investigator

Central Contact

Susan Carnell, PhD

✉ susan.carnell@jhmi.edu

📞 410-955-7192

Principal Investigator

Susan Carnell, PhD

PRINCIPAL INVESTIGATOR

Johns Hopkins University

Frequently Asked Questions

Who can join the NCT06861868 clinical trial?

This trial is open to participants of all sexes, aged 7 Years or older, up to 12 Years, studying Obesity and Overweight. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06861868 currently recruiting?

Yes, NCT06861868 is actively recruiting participants. Contact the research team at susan.carnell@jhmi.edu for enrollment information.

Where is the NCT06861868 trial being conducted?

This trial is being conducted at Baltimore, United States, Baltimore, United States, Providence, United States, Seattle, United States.

Who is sponsoring the NCT06861868 clinical trial?

NCT06861868 is sponsored by Johns Hopkins University. The principal investigator is Susan Carnell, PhD at Johns Hopkins University. The trial plans to enroll 210 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology