← Back to Clinical Trials
Recruiting NCT06861868

Brain and Behavior Influences on Obesity Development From Infancy Through Childhood

Trial Parameters

Condition Obesity and Overweight
Sponsor Johns Hopkins University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 210
Sex ALL
Min Age 7 Years
Max Age 12 Years
Start Date 2024-12-02
Completion 2029-03-31

Brief Summary

The investigators project, RESONATE, aims to investigate why some children develop obesity. To do this it uses data on eating and eating-related behaviors, genetic and environmental factors, and brain structure and function. This data is collected in a sub-sample of RESONANCE, a large study of families of children from infancy through childhood. The results will lay foundations for the development of early interventions to prevent or treat obesity.

Eligibility Criteria

Inclusion Criteria: * Participants from the RESONANCE cohort are eligible if the participant will reach 7-12 years of age during the proposed project period and have no food allergies. Exclusion Criteria: * Exclusion criteria for RESONANCE include: 1. In utero exposure to alcohol, cigarette, or illicit substances; 2. First trimester fetal US abnormalities; 3. Complicated pregnancy (e.g., pre-eclampsia); 4. Complicated delivery, including APGAR scores less than 8 and/or neonatal intensive care unit (NICU) admission; 5. History of neurological (e.g., epilepsy), psychiatric (e.g., anxiety or depression requiring treatment with medication) or developmental disorder (e.g., autism spectrum disorder (ASD), dyslexia); 6. Contraindications for MRI including metal in the body, claustrophobia.

Related Trials