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Recruiting NCT05646485

NCT05646485 Bladder Cancer Screening Trial

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Clinical Trial Summary
NCT ID NCT05646485
Status Recruiting
Phase
Sponsor University of Texas Southwestern Medical Center
Condition Bladder Cancer
Study Type INTERVENTIONAL
Enrollment 1,000 participants
Start Date 2023-05-05
Primary Completion 2027-04

Eligibility & Interventions

Sex All sexes
Min Age 50 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Urinalysis

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 1,000 participants in total. It began in 2023-05-05 with a primary completion date of 2027-04.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

There is currently no accepted screening strategy for patients at high risk of developing bladder cancer. This study will ask patients to complete a urine test every 6 months for 2 years to help assess if routine screening helps finding bladder cancer at an earlier stage.

Eligibility Criteria

Inclusion Criteria: * Age ≥ 50 * Smoking: ≥15 pack-year smoking history * Occupation:≥ 15 years of occupational exposures including: textile worker, painter, dry cleaners Exclusion Criteria: * Prior history of bladder, kidney, or prostate cancer * Prior evaluation of micro or gross hematuria within the last 2 years * Do not provide informed consent

Contact & Investigator

Central Contact

Yair Lotan, MD

✉ yair.lotan@UTsouthwestern.edu

📞 214-648-0389

Principal Investigator

Yair Lotan, MD

PRINCIPAL INVESTIGATOR

University of Texas Southwestern Medical Center

Frequently Asked Questions

Who can join the NCT05646485 clinical trial?

This trial is open to participants of all sexes, aged 50 Years or older, studying Bladder Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05646485 currently recruiting?

Yes, NCT05646485 is actively recruiting participants. Contact the research team at yair.lotan@UTsouthwestern.edu for enrollment information.

Where is the NCT05646485 trial being conducted?

This trial is being conducted at Dallas, United States.

Who is sponsoring the NCT05646485 clinical trial?

NCT05646485 is sponsored by University of Texas Southwestern Medical Center. The principal investigator is Yair Lotan, MD at University of Texas Southwestern Medical Center. The trial plans to enroll 1,000 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology