← Back to Clinical Trials
Recruiting NCT05281237

NCT05281237 Avecure Flexible Microwave Ablation Probe For Lung Nodules

◆ AI Clinical Summary
Plain-language summary for patients
Clinical Trial Summary
NCT ID NCT05281237
Status Recruiting
Phase
Sponsor Beth Israel Deaconess Medical Center
Condition Stage I - II Primary Lung Cancer
Study Type INTERVENTIONAL
Enrollment 10 participants
Start Date 2022-06-01
Primary Completion 2026-12-30

Eligibility & Interventions

Sex All sexes
Min Age 22 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
AveCure 16 Gauge Flexible Microwave Ablation Probe

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 10 participants in total. It began in 2022-06-01 with a primary completion date of 2026-12-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This research study to determine the effectiveness of the AveCure Flexible Microwave Ablation Probe to destroy cancerous lung nodules up to 3 c m in size. This research study involves microwave ablation (MWA)

Eligibility Criteria

Inclusion Criteria: * Subject with Stage I - II primary lung cancer (Solitary nodules up to 3 cm) as defined by previous pathology or ROSE. * Pathological proof of target nodule/tumor type and malignancy with specimen considered adequate per institutional laboratory standards * Target nodule/tumor which can be accessed via navigational bronchoscopy and confirmed location with cone beam CT scan intra-operatively * Resection/surgical candidate (lobectomy or greater) * Participants must be at least 22 years old and able to provide consent Exclusion Criteria: * Subjects in whom flexible bronchoscopy is contraindicated * Target nodule \< 1.0 cm * Prior radiation or neo adjuvant chemotherapy of the target nodule/tumor * Any comorbidity that the investigator feels would interfere with the safety of the subject or the evaluation of study objectives * Pacemaker, implantable cardioverter, or another electronic implantable device * Patient cannot tolerate bronchoscopy * Patients with coagulopathy * Patients in other therapeutic lung cancer studies * Subject is pregnant or breastfeeding * COVID-19 positive patient at the time of procedure.

Contact & Investigator

Central Contact

Jason Beattie, MD

✉ jbeattie@bidmc.harvard.edu

📞 (617) 632- 8252

Principal Investigator

Jason Beattie, MD

PRINCIPAL INVESTIGATOR

Beth Israel Deaconess Medical Center

Frequently Asked Questions

Who can join the NCT05281237 clinical trial?

This trial is open to participants of all sexes, aged 22 Years or older, studying Stage I - II Primary Lung Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05281237 currently recruiting?

Yes, NCT05281237 is actively recruiting participants. Contact the research team at jbeattie@bidmc.harvard.edu for enrollment information.

Where is the NCT05281237 trial being conducted?

This trial is being conducted at Boston, United States.

Who is sponsoring the NCT05281237 clinical trial?

NCT05281237 is sponsored by Beth Israel Deaconess Medical Center. The principal investigator is Jason Beattie, MD at Beth Israel Deaconess Medical Center. The trial plans to enroll 10 participants.

Related Trials

Related Intelligence Guides

In-depth guides covering this condition's trials, eligibility, and what to expect.

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology